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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

1FL7

HUMAN FOLLICLE STIMULATING HORMONE

Functional Information from GO Data
ChainGOidnamespacecontents
A0005179molecular_functionhormone activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005796cellular_componentGolgi lumen
A0007186biological_processG protein-coupled receptor signaling pathway
A0008284biological_processpositive regulation of cell population proliferation
A0009755biological_processhormone-mediated signaling pathway
A0010469biological_processregulation of signaling receptor activity
A0010893biological_processpositive regulation of steroid biosynthetic process
A0016913molecular_functionfollicle-stimulating hormone activity
A0016914cellular_componentfollicle-stimulating hormone complex
A0030335biological_processpositive regulation of cell migration
A0042699biological_processfollicle-stimulating hormone signaling pathway
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0061696cellular_componentpituitary gonadotropin complex
B0001541biological_processovarian follicle development
B0005102molecular_functionsignaling receptor binding
B0005179molecular_functionhormone activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0006701biological_processprogesterone biosynthetic process
B0007165biological_processsignal transduction
B0007179biological_processtransforming growth factor beta receptor signaling pathway
B0007186biological_processG protein-coupled receptor signaling pathway
B0007292biological_processfemale gamete generation
B0007565biological_processfemale pregnancy
B0008284biological_processpositive regulation of cell population proliferation
B0010893biological_processpositive regulation of steroid biosynthetic process
B0016913molecular_functionfollicle-stimulating hormone activity
B0016914cellular_componentfollicle-stimulating hormone complex
B0030335biological_processpositive regulation of cell migration
B0042699biological_processfollicle-stimulating hormone signaling pathway
B0045944biological_processpositive regulation of transcription by RNA polymerase II
C0005179molecular_functionhormone activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005796cellular_componentGolgi lumen
C0007186biological_processG protein-coupled receptor signaling pathway
C0008284biological_processpositive regulation of cell population proliferation
C0009755biological_processhormone-mediated signaling pathway
C0010469biological_processregulation of signaling receptor activity
C0010893biological_processpositive regulation of steroid biosynthetic process
C0016913molecular_functionfollicle-stimulating hormone activity
C0016914cellular_componentfollicle-stimulating hormone complex
C0030335biological_processpositive regulation of cell migration
C0042699biological_processfollicle-stimulating hormone signaling pathway
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0061696cellular_componentpituitary gonadotropin complex
D0001541biological_processovarian follicle development
D0005102molecular_functionsignaling receptor binding
D0005179molecular_functionhormone activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005737cellular_componentcytoplasm
D0006701biological_processprogesterone biosynthetic process
D0007165biological_processsignal transduction
D0007179biological_processtransforming growth factor beta receptor signaling pathway
D0007186biological_processG protein-coupled receptor signaling pathway
D0007292biological_processfemale gamete generation
D0007565biological_processfemale pregnancy
D0008284biological_processpositive regulation of cell population proliferation
D0010893biological_processpositive regulation of steroid biosynthetic process
D0016913molecular_functionfollicle-stimulating hormone activity
D0016914cellular_componentfollicle-stimulating hormone complex
D0030335biological_processpositive regulation of cell migration
D0042699biological_processfollicle-stimulating hormone signaling pathway
D0045944biological_processpositive regulation of transcription by RNA polymerase II
Functional Information from PROSITE/UniProt
site_idPS00261
Number of Residues7
DetailsGLYCO_HORMONE_BETA_1 Glycoprotein hormones beta chain signature 1. CAGYCyT
ChainResidueDetails
BCYS28-THR34
site_idPS00689
Number of Residues28
DetailsGLYCO_HORMONE_BETA_2 Glycoprotein hormones beta chain signature 2. PVAtqChCgkCdsdsTDCtvrglg..PsyC
ChainResidueDetails
BPRO77-CYS104
site_idPS00779
Number of Residues13
DetailsGLYCO_HORMONE_ALPHA_1 Glycoprotein hormones alpha chain signature 1. CmGCCFSRAYPTP
ChainResidueDetails
ACYS28-PRO40
site_idPS00780
Number of Residues14
DetailsGLYCO_HORMONE_ALPHA_2 Glycoprotein hormones alpha chain signature 2. NHTaChCsTCyyHK
ChainResidueDetails
AASN78-LYS91
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000036","evidences":[{"source":"PubMed","id":"15662415","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24692546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MQW","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000037","evidences":[{"source":"PubMed","id":"15662415","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24692546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MQW","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15662415","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"4835136","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MQW","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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