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1FL7

HUMAN FOLLICLE STIMULATING HORMONE

Functional Information from GO Data
ChainGOidnamespacecontents
A0005179molecular_functionhormone activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005796cellular_componentGolgi lumen
A0006590biological_processthyroid hormone generation
A0007186biological_processG protein-coupled receptor signaling pathway
A0008284biological_processpositive regulation of cell population proliferation
A0008406biological_processgonad development
A0009755biological_processhormone-mediated signaling pathway
A0010469biological_processregulation of signaling receptor activity
A0010893biological_processpositive regulation of steroid biosynthetic process
A0016913molecular_functionfollicle-stimulating hormone activity
A0016914cellular_componentfollicle-stimulating hormone complex
A0030335biological_processpositive regulation of cell migration
A0030878biological_processthyroid gland development
A0032275biological_processluteinizing hormone secretion
A0032870biological_processcellular response to hormone stimulus
A0035265biological_processorgan growth
A0042699biological_processfollicle-stimulating hormone signaling pathway
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046621biological_processnegative regulation of organ growth
A0046884biological_processfollicle-stimulating hormone secretion
A0048589biological_processdevelopmental growth
A0061696cellular_componentpituitary gonadotropin complex
B0001541biological_processovarian follicle development
B0005179molecular_functionhormone activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0006701biological_processprogesterone biosynthetic process
B0007179biological_processtransforming growth factor beta receptor signaling pathway
B0007186biological_processG protein-coupled receptor signaling pathway
B0007283biological_processspermatogenesis
B0007292biological_processfemale gamete generation
B0007565biological_processfemale pregnancy
B0008284biological_processpositive regulation of cell population proliferation
B0010469biological_processregulation of signaling receptor activity
B0010628biological_processpositive regulation of gene expression
B0010893biological_processpositive regulation of steroid biosynthetic process
B0016913molecular_functionfollicle-stimulating hormone activity
B0016914cellular_componentfollicle-stimulating hormone complex
B0030335biological_processpositive regulation of cell migration
B0042699biological_processfollicle-stimulating hormone signaling pathway
B0045670biological_processregulation of osteoclast differentiation
B0045780biological_processpositive regulation of bone resorption
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0060011biological_processSertoli cell proliferation
C0005179molecular_functionhormone activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005796cellular_componentGolgi lumen
C0006590biological_processthyroid hormone generation
C0007186biological_processG protein-coupled receptor signaling pathway
C0008284biological_processpositive regulation of cell population proliferation
C0008406biological_processgonad development
C0009755biological_processhormone-mediated signaling pathway
C0010469biological_processregulation of signaling receptor activity
C0010893biological_processpositive regulation of steroid biosynthetic process
C0016913molecular_functionfollicle-stimulating hormone activity
C0016914cellular_componentfollicle-stimulating hormone complex
C0030335biological_processpositive regulation of cell migration
C0030878biological_processthyroid gland development
C0032275biological_processluteinizing hormone secretion
C0032870biological_processcellular response to hormone stimulus
C0035265biological_processorgan growth
C0042699biological_processfollicle-stimulating hormone signaling pathway
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0046621biological_processnegative regulation of organ growth
C0046884biological_processfollicle-stimulating hormone secretion
C0048589biological_processdevelopmental growth
C0061696cellular_componentpituitary gonadotropin complex
D0001541biological_processovarian follicle development
D0005179molecular_functionhormone activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005737cellular_componentcytoplasm
D0006701biological_processprogesterone biosynthetic process
D0007179biological_processtransforming growth factor beta receptor signaling pathway
D0007186biological_processG protein-coupled receptor signaling pathway
D0007283biological_processspermatogenesis
D0007292biological_processfemale gamete generation
D0007565biological_processfemale pregnancy
D0008284biological_processpositive regulation of cell population proliferation
D0010469biological_processregulation of signaling receptor activity
D0010628biological_processpositive regulation of gene expression
D0010893biological_processpositive regulation of steroid biosynthetic process
D0016913molecular_functionfollicle-stimulating hormone activity
D0016914cellular_componentfollicle-stimulating hormone complex
D0030335biological_processpositive regulation of cell migration
D0042699biological_processfollicle-stimulating hormone signaling pathway
D0045670biological_processregulation of osteoclast differentiation
D0045780biological_processpositive regulation of bone resorption
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D0060011biological_processSertoli cell proliferation
Functional Information from PROSITE/UniProt
site_idPS00261
Number of Residues7
DetailsGLYCO_HORMONE_BETA_1 Glycoprotein hormones beta chain signature 1. CAGYCyT
ChainResidueDetails
BCYS28-THR34

site_idPS00689
Number of Residues28
DetailsGLYCO_HORMONE_BETA_2 Glycoprotein hormones beta chain signature 2. PVAtqChCgkCdsdsTDCtvrglg..PsyC
ChainResidueDetails
BPRO77-CYS104

site_idPS00779
Number of Residues13
DetailsGLYCO_HORMONE_ALPHA_1 Glycoprotein hormones alpha chain signature 1. CmGCCFSRAYPTP
ChainResidueDetails
ACYS28-PRO40

site_idPS00780
Number of Residues14
DetailsGLYCO_HORMONE_ALPHA_2 Glycoprotein hormones alpha chain signature 2. NHTaChCsTCyyHK
ChainResidueDetails
AASN78-LYS91

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15662415, ECO:0000269|PubMed:4835136, ECO:0007744|PDB:4MQW
ChainResidueDetails
BASN7
BASN24
DASN7
DASN24

226707

PDB entries from 2024-10-30

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