1FIF
N-ACETYLGALACTOSAMINE-SELECTIVE MUTANT OF MANNOSE-BINDING PROTEIN-A (QPDWG-HDRPY)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001867 | biological_process | complement activation, lectin pathway |
| A | 0005537 | molecular_function | mannose binding |
| B | 0001867 | biological_process | complement activation, lectin pathway |
| B | 0005537 | molecular_function | mannose binding |
| C | 0001867 | biological_process | complement activation, lectin pathway |
| C | 0005537 | molecular_function | mannose binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1 |
| Chain | Residue |
| A | ASP161 |
| A | GLU165 |
| A | ASP188 |
| A | GLU198 |
| A | ASP199 |
| A | HOH554 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 2 |
| Chain | Residue |
| A | ASN210 |
| A | ASP211 |
| A | HOH439 |
| A | HOH444 |
| A | GLN185 |
| A | ASP187 |
| A | GLU198 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 3 |
| Chain | Residue |
| A | GLU84 |
| A | GLU165 |
| A | ASP199 |
| A | HOH416 |
| A | HOH555 |
| A | HOH558 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 415 |
| Chain | Residue |
| A | ASP199 |
| A | SER213 |
| A | CYS214 |
| A | HOH516 |
| A | HOH556 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 1 |
| Chain | Residue |
| B | ASP161 |
| B | GLU165 |
| B | ASP188 |
| B | GLU198 |
| B | ASP199 |
| B | HOH364 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 2 |
| Chain | Residue |
| B | GLN185 |
| B | ASP187 |
| B | GLU198 |
| B | ASP211 |
| B | HOH275 |
| B | HOH363 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 3 |
| Chain | Residue |
| B | GLU165 |
| B | ASP199 |
| B | HOH231 |
| B | HOH362 |
| B | HOH365 |
| B | HOH366 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1 |
| Chain | Residue |
| C | ASP161 |
| C | GLU165 |
| C | ASP188 |
| C | GLU198 |
| C | ASP199 |
| C | HOH534 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 2 |
| Chain | Residue |
| C | GLN185 |
| C | ASP187 |
| C | GLU198 |
| C | ASN210 |
| C | ASP211 |
| C | HOH428 |
| C | HOH459 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 3 |
| Chain | Residue |
| A | HOH557 |
| C | GLU84 |
| C | GLU165 |
| C | ASP199 |
| C | HOH535 |
| C | HOH536 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 416 |
| Chain | Residue |
| C | ASP199 |
| C | CYS214 |
Functional Information from PROSITE/UniProt
| site_id | PS00615 |
| Number of Residues | 23 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CVhivdngl.....WNDDSCqrpyt.AVC |
| Chain | Residue | Details |
| A | CYS200-CYS222 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB |
| Chain | Residue | Details |
| B | ASP199 | |
| A | ASP161 | |
| A | GLU165 | |
| A | ASP188 | |
| A | ASP199 | |
| B | ASP161 | |
| B | GLU165 | |
| B | ASP188 | |
| C | ASP161 | |
| C | GLU165 | |
| C | ASP188 | |
| C | ASP199 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB |
| Chain | Residue | Details |
| A | GLN185 | |
| A | ASP187 | |
| A | GLU198 | |
| A | ASN210 | |
| A | ASP211 | |
| B | GLN185 | |
| B | ASP187 | |
| B | GLU198 | |
| B | ASN210 | |
| B | ASP211 | |
| C | GLN185 | |
| C | ASP187 | |
| C | GLU198 | |
| C | ASN210 | |
| C | ASP211 |
