1FIF

N-ACETYLGALACTOSAMINE-SELECTIVE MUTANT OF MANNOSE-BINDING PROTEIN-A (QPDWG-HDRPY)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001867	biological_process	complement activation, lectin pathway
A	0005537	molecular_function	mannose binding
B	0001867	biological_process	complement activation, lectin pathway
B	0005537	molecular_function	mannose binding
C	0001867	biological_process	complement activation, lectin pathway
C	0005537	molecular_function	mannose binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1

Chain	Residue
A	ASP161
A	GLU165
A	ASP188
A	GLU198
A	ASP199
A	HOH554

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 2

Chain	Residue
A	ASN210
A	ASP211
A	HOH439
A	HOH444
A	GLN185
A	ASP187
A	GLU198

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 3

Chain	Residue
A	GLU84
A	GLU165
A	ASP199
A	HOH416
A	HOH555
A	HOH558

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 415

Chain	Residue
A	ASP199
A	SER213
A	CYS214
A	HOH516
A	HOH556

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1

Chain	Residue
B	ASP161
B	GLU165
B	ASP188
B	GLU198
B	ASP199
B	HOH364

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 2

Chain	Residue
B	GLN185
B	ASP187
B	GLU198
B	ASP211
B	HOH275
B	HOH363

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 3

Chain	Residue
B	GLU165
B	ASP199
B	HOH231
B	HOH362
B	HOH365
B	HOH366

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 1

Chain	Residue
C	ASP161
C	GLU165
C	ASP188
C	GLU198
C	ASP199
C	HOH534

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA C 2

Chain	Residue
C	GLN185
C	ASP187
C	GLU198
C	ASN210
C	ASP211
C	HOH428
C	HOH459

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 3

Chain	Residue
A	HOH557
C	GLU84
C	GLU165
C	ASP199
C	HOH535
C	HOH536

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 416

Chain	Residue
C	ASP199
C	CYS214

---

Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	23
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVhivdngl.....WNDDSCqrpyt.AVC

Chain	Residue	Details
A	CYS200-CYS222

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7704532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AFA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AFB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BCH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BCJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2MSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KMB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7704532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2MSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KMB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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