1FHB
THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE CYANIDE ADDUCT OF A MET80ALA VARIANT OF SACCHAROMYCES CEREVISIAE ISO-1-CYTOCHROME C. IDENTIFICATION OF LIGAND-RESIDUE INTERACTIONS IN THE DISTAL HEME CAVITY
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1901612 | molecular_function | cardiolipin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CYN A 105 |
| Chain | Residue |
| A | TYR67 |
| A | PRO71 |
| A | ALA80 |
| A | HEM104 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM A 104 |
| Chain | Residue |
| A | VAL28 |
| A | GLY29 |
| A | PRO30 |
| A | LEU32 |
| A | ILE35 |
| A | SER40 |
| A | GLY41 |
| A | TYR46 |
| A | THR49 |
| A | ASN52 |
| A | TRP59 |
| A | MET64 |
| A | TYR67 |
| A | LEU68 |
| A | GLY77 |
| A | THR78 |
| A | ALA80 |
| A | PHE82 |
| A | LEU85 |
| A | LEU94 |
| A | LEU98 |
| A | CYN105 |
| A | ARG13 |
| A | CYS14 |
| A | GLN16 |
| A | CYS17 |
| A | HIS18 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: covalent => ECO:0000269|PubMed:11880631, ECO:0000269|PubMed:18390544, ECO:0007744|PDB:1KYO, ECO:0007744|PDB:3CX5 |
| Chain | Residue | Details |
| A | LEU15 | |
| A | HIS18 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:11880631, ECO:0000269|PubMed:18390544, ECO:0007744|PDB:1KYO, ECO:0007744|PDB:3CX5 |
| Chain | Residue | Details |
| A | THR19 | |
| A | ALA81 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6,N6,N6-trimethyllysine; by CTM1 => ECO:0000269|PubMed:10791961, ECO:0000269|PubMed:11880631, ECO:0007744|PDB:1KYO |
| Chain | Residue | Details |
| A | LYS73 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:10821864, ECO:0000269|PubMed:18390544 |
| Chain | Residue | Details |
| A | TYR74 |
