Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004322 | molecular_function | ferroxidase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0006880 | biological_process | intracellular sequestering of iron ion |
| A | 0006955 | biological_process | immune response |
| A | 0008043 | cellular_component | intracellular ferritin complex |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0008285 | biological_process | negative regulation of cell population proliferation |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044754 | cellular_component | autolysosome |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048147 | biological_process | negative regulation of fibroblast proliferation |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0140315 | molecular_function | iron ion sequestering activity |
| A | 1904724 | cellular_component | tertiary granule lumen |
| A | 1904813 | cellular_component | ficolin-1-rich granule lumen |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 200 |
| Chain | Residue |
| A | GLU27 |
| A | GLU62 |
| A | HIS65 |
| A | HOH223 |
| A | HOH224 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 210 |
| Chain | Residue |
| A | ASP84 |
| A | ASP84 |
| A | GLN86 |
| A | GLN86 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 211 |
| Chain | Residue |
| A | GLU134 |
| A | GLU134 |
| A | GLU134 |
| A | HOH229 |
| A | HOH229 |
| A | HOH229 |
Functional Information from PROSITE/UniProt
| site_id | PS00204 |
| Number of Residues | 21 |
| Details | FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFIEthYLneqvkaIK |
| Chain | Residue | Details |
| A | ASP126-LYS146 | |
| site_id | PS00540 |
| Number of Residues | 19 |
| Details | FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKLMklQNqRgGR |
| Chain | Residue | Details |
| A | GLU61-ARG79 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU28 | |
| A | ALA66 | |
| Chain | Residue | Details |
| A | ARG63 | |
| A | LYS108 | |
| A | VAL142 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine; in Ferritin heavy chain, N-terminally processed => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | ASP187 | |
| Chain | Residue | Details |
| A | SER190 | |
