1FF3

STRUCTURE OF THE PEPTIDE METHIONINE SULFOXIDE REDUCTASE FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0008113	molecular_function	peptide-methionine (S)-S-oxide reductase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016671	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
A	0030091	biological_process	protein repair
A	0033744	molecular_function	L-methionine:thioredoxin-disulfide S-oxidoreductase activity
A	0034599	biological_process	cellular response to oxidative stress
A	0036211	biological_process	protein modification process
A	0036456	molecular_function	L-methionine-(S)-S-oxide reductase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0008113	molecular_function	peptide-methionine (S)-S-oxide reductase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016671	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
B	0030091	biological_process	protein repair
B	0033744	molecular_function	L-methionine:thioredoxin-disulfide S-oxidoreductase activity
B	0034599	biological_process	cellular response to oxidative stress
B	0036211	biological_process	protein modification process
B	0036456	molecular_function	L-methionine-(S)-S-oxide reductase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0008113	molecular_function	peptide-methionine (S)-S-oxide reductase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016671	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
C	0030091	biological_process	protein repair
C	0033744	molecular_function	L-methionine:thioredoxin-disulfide S-oxidoreductase activity
C	0034599	biological_process	cellular response to oxidative stress
C	0036211	biological_process	protein modification process
C	0036456	molecular_function	L-methionine-(S)-S-oxide reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 533

Chain	Residue
A	THR81
A	ARG83
A	HOH602
A	HOH639

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 534

Chain	Residue
A	SER1
A	LYS5
A	LYS6
A	HIS7
B	HIS7

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 535

Chain	Residue
A	ARG18
A	ASN19
A	THR20
A	HOH759

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 536

Chain	Residue
B	ARG18
B	ASN19
B	THR20

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000269|PubMed:10964927

Chain	Residue	Details
A	PHE52
B	PHE52
C	PHE52

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