1FD8

SOLUTION STRUCTURE OF THE CU(I) FORM OF THE YEAST METALLOCHAPERONE, ATX1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006811	biological_process	monoatomic ion transport
A	0006825	biological_process	copper ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0016531	molecular_function	copper chaperone activity
A	0034599	biological_process	cellular response to oxidative stress
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU1 A 74

Chain	Residue
A	THR14
A	CYS15
A	CYS18
A	LYS65

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Functional Information from PROSITE/UniProt

site_id	PS01047
Number of Residues	31
Details	HMA_1 Heavy-metal-associated domain. NvVMtCsGCsgaVNkvLtklepdvskidIsL

Chain	Residue	Details
A	ASN10-LEU40

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Domain: {"description":"HMA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00280","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00280","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11327811","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19965379","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28865724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3K7R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5VDF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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