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1FCZ

ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0048384biological_processretinoic acid receptor signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE 156 A 450
ChainResidue
APHE201
APHE304
ALEU400
AHOH549
AALA234
ALEU268
ALEU271
AMET272
AILE275
AARG278
APHE288
ASER289

site_idAC2
Number of Residues17
DetailsBINDING SITE FOR RESIDUE LMU A 451
ChainResidue
ALYS236
ALYS240
AGLU243
ALEU263
ALYS264
ACYS267
AASP340
AGLN354
ALEU380
AILE383
ATHR384
AARG387
AHOH561
AHOH607
AHOH683
AHOH732
AHOH760

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS401

223532

PDB entries from 2024-08-07

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