1F9W
CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003777 | molecular_function | microtubule motor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0007018 | biological_process | microtubule-based movement |
| A | 0008017 | molecular_function | microtubule binding |
| B | 0003777 | molecular_function | microtubule motor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0007018 | biological_process | microtubule-based movement |
| B | 0008017 | molecular_function | microtubule binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 996 |
| Chain | Residue |
| A | THR481 |
| A | ADP998 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG B 997 |
| Chain | Residue |
| B | THR481 |
| B | ADP999 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP A 998 |
| Chain | Residue |
| A | GLY477 |
| A | SER478 |
| A | GLY479 |
| A | LYS480 |
| A | THR481 |
| A | PHE482 |
| A | MG996 |
| A | HOH1003 |
| A | ARG392 |
| A | ARG394 |
| A | PRO395 |
| A | GLN475 |
| A | THR476 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP B 999 |
| Chain | Residue |
| B | ARG392 |
| B | ARG394 |
| B | PRO395 |
| B | GLN475 |
| B | THR476 |
| B | GLY477 |
| B | SER478 |
| B | GLY479 |
| B | LYS480 |
| B | THR481 |
| B | PHE482 |
| B | MG997 |
| B | HOH1050 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11387196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F9V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11387196","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22734002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9485302","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F9T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F9U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F9W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ETP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11387196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F9W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22734002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ETP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1goj |
| Chain | Residue | Details |
| A | GLY629 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1goj |
| Chain | Residue | Details |
| B | GLY629 |
