Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004024 | molecular_function | alcohol dehydrogenase (NAD+) activity, zinc-dependent |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046294 | biological_process | formaldehyde catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051903 | molecular_function | S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 372 |
| Chain | Residue |
| A | CYS44 |
| A | HIS65 |
| A | CYS173 |
| A | EOH374 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 373 |
| Chain | Residue |
| A | CYS94 |
| A | GLY95 |
| A | CYS97 |
| A | CYS100 |
| A | CYS108 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 376 |
| Chain | Residue |
| A | THR79 |
| A | ARG114 |
| A | SER121 |
| A | ARG152 |
| A | HOH580 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 377 |
| Chain | Residue |
| A | LYS323 |
| A | GLU327 |
| A | ARG330 |
| A | HOH411 |
| A | HOH535 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NAD A 375 |
| Chain | Residue |
| A | HIS45 |
| A | THR46 |
| A | THR177 |
| A | GLY200 |
| A | ALA201 |
| A | VAL202 |
| A | ASP222 |
| A | ARG227 |
| A | SER265 |
| A | THR266 |
| A | VAL288 |
| A | VAL314 |
| A | VAL315 |
| A | GLU316 |
| A | EOH374 |
| A | HOH387 |
| A | HOH388 |
| A | HOH443 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EOH A 374 |
| Chain | Residue |
| A | THR46 |
| A | PHE140 |
| A | CYS173 |
| A | GLU316 |
| A | ZN372 |
| A | NAD375 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEgSGIieaiGpnV |
| Chain | Residue | Details |
| A | GLY64-VAL78 | |
