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1F3C

REFINED SOLUTION STRUCTURE OF 8KDA DYNEIN LIGHT CHAIN (DLC8)

Replaces:  1BKQ
Functional Information from GO Data
ChainGOidnamespacecontents
A0000776cellular_componentkinetochore
A0004857molecular_functionenzyme inhibitor activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005868cellular_componentcytoplasmic dynein complex
A0005874cellular_componentmicrotubule
A0005875cellular_componentmicrotubule associated complex
A0005929cellular_componentcilium
A0006915biological_processapoptotic process
A0006974biological_processDNA damage response
A0007017biological_processmicrotubule-based process
A0007286biological_processspermatid development
A0008180cellular_componentCOP9 signalosome
A0015630cellular_componentmicrotubule cytoskeleton
A0016020cellular_componentmembrane
A0019899molecular_functionenzyme binding
A0019904molecular_functionprotein domain specific binding
A0030141cellular_componentsecretory granule
A0030235molecular_functionnitric-oxide synthase regulator activity
A0030286cellular_componentdynein complex
A0035721biological_processintraciliary retrograde transport
A0035774biological_processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
A0035861cellular_componentsite of double-strand break
A0036487molecular_functionnitric-oxide synthase inhibitor activity
A0042326biological_processnegative regulation of phosphorylation
A0042802molecular_functionidentical protein binding
A0044458biological_processmotile cilium assembly
A0044877molecular_functionprotein-containing complex binding
A0045019biological_processnegative regulation of nitric oxide biosynthetic process
A0045505molecular_functiondynein intermediate chain binding
A0051881biological_processregulation of mitochondrial membrane potential
A0060703molecular_functiondeoxyribonuclease inhibitor activity
A0072686cellular_componentmitotic spindle
A0097110molecular_functionscaffold protein binding
A0110027biological_processnegative regulation of DNA strand resection involved in replication fork processing
A0160040biological_processmitocytosis
A1902857biological_processpositive regulation of non-motile cilium assembly
A1904115cellular_componentaxon cytoplasm
B0000776cellular_componentkinetochore
B0004857molecular_functionenzyme inhibitor activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005694cellular_componentchromosome
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005813cellular_componentcentrosome
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005868cellular_componentcytoplasmic dynein complex
B0005874cellular_componentmicrotubule
B0005875cellular_componentmicrotubule associated complex
B0005929cellular_componentcilium
B0006915biological_processapoptotic process
B0006974biological_processDNA damage response
B0007017biological_processmicrotubule-based process
B0007286biological_processspermatid development
B0008180cellular_componentCOP9 signalosome
B0015630cellular_componentmicrotubule cytoskeleton
B0016020cellular_componentmembrane
B0019899molecular_functionenzyme binding
B0019904molecular_functionprotein domain specific binding
B0030141cellular_componentsecretory granule
B0030235molecular_functionnitric-oxide synthase regulator activity
B0030286cellular_componentdynein complex
B0035721biological_processintraciliary retrograde transport
B0035774biological_processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
B0035861cellular_componentsite of double-strand break
B0036487molecular_functionnitric-oxide synthase inhibitor activity
B0042326biological_processnegative regulation of phosphorylation
B0042802molecular_functionidentical protein binding
B0044458biological_processmotile cilium assembly
B0044877molecular_functionprotein-containing complex binding
B0045019biological_processnegative regulation of nitric oxide biosynthetic process
B0045505molecular_functiondynein intermediate chain binding
B0051881biological_processregulation of mitochondrial membrane potential
B0060703molecular_functiondeoxyribonuclease inhibitor activity
B0072686cellular_componentmitotic spindle
B0097110molecular_functionscaffold protein binding
B0110027biological_processnegative regulation of DNA strand resection involved in replication fork processing
B0160040biological_processmitocytosis
B1902857biological_processpositive regulation of non-motile cilium assembly
B1904115cellular_componentaxon cytoplasm
Functional Information from PROSITE/UniProt
site_idPS01239
Number of Residues15
DetailsDYNEIN_LIGHT_1 Dynein light chain type 1 signature. HcIvGRnFGSyVTHE
ChainResidueDetails
AHIS55-GLU69

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P63167
ChainResidueDetails
ALYS36
BLYS36

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63167
ChainResidueDetails
ASER88
BSER88

site_idSWS_FT_FI3
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P63167
ChainResidueDetails
ALYS43
BLYS43

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PDB entries from 2024-07-24

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