Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1F1H

CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006541	biological_process	glutamine metabolic process
A	0006542	biological_process	glutamine biosynthetic process
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0019740	biological_process	nitrogen utilization
A	0030145	molecular_function	manganese ion binding
A	0046872	molecular_function	metal ion binding
A	0051260	biological_process	protein homooligomerization
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006541	biological_process	glutamine metabolic process
B	0006542	biological_process	glutamine biosynthetic process
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0019740	biological_process	nitrogen utilization
B	0030145	molecular_function	manganese ion binding
B	0046872	molecular_function	metal ion binding
B	0051260	biological_process	protein homooligomerization
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006541	biological_process	glutamine metabolic process
C	0006542	biological_process	glutamine biosynthetic process
C	0016020	cellular_component	membrane
C	0016874	molecular_function	ligase activity
C	0019740	biological_process	nitrogen utilization
C	0030145	molecular_function	manganese ion binding
C	0046872	molecular_function	metal ion binding
C	0051260	biological_process	protein homooligomerization
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006541	biological_process	glutamine metabolic process
D	0006542	biological_process	glutamine biosynthetic process
D	0016020	cellular_component	membrane
D	0016874	molecular_function	ligase activity
D	0019740	biological_process	nitrogen utilization
D	0030145	molecular_function	manganese ion binding
D	0046872	molecular_function	metal ion binding
D	0051260	biological_process	protein homooligomerization
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0004356	molecular_function	glutamine synthetase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006541	biological_process	glutamine metabolic process
E	0006542	biological_process	glutamine biosynthetic process
E	0016020	cellular_component	membrane
E	0016874	molecular_function	ligase activity
E	0019740	biological_process	nitrogen utilization
E	0030145	molecular_function	manganese ion binding
E	0046872	molecular_function	metal ion binding
E	0051260	biological_process	protein homooligomerization
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0004356	molecular_function	glutamine synthetase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006541	biological_process	glutamine metabolic process
F	0006542	biological_process	glutamine biosynthetic process
F	0016020	cellular_component	membrane
F	0016874	molecular_function	ligase activity
F	0019740	biological_process	nitrogen utilization
F	0030145	molecular_function	manganese ion binding
F	0046872	molecular_function	metal ion binding
F	0051260	biological_process	protein homooligomerization
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0004356	molecular_function	glutamine synthetase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006541	biological_process	glutamine metabolic process
G	0006542	biological_process	glutamine biosynthetic process
G	0016020	cellular_component	membrane
G	0016874	molecular_function	ligase activity
G	0019740	biological_process	nitrogen utilization
G	0030145	molecular_function	manganese ion binding
G	0046872	molecular_function	metal ion binding
G	0051260	biological_process	protein homooligomerization
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0004356	molecular_function	glutamine synthetase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006541	biological_process	glutamine metabolic process
H	0006542	biological_process	glutamine biosynthetic process
H	0016020	cellular_component	membrane
H	0016874	molecular_function	ligase activity
H	0019740	biological_process	nitrogen utilization
H	0030145	molecular_function	manganese ion binding
H	0046872	molecular_function	metal ion binding
H	0051260	biological_process	protein homooligomerization
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0004356	molecular_function	glutamine synthetase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0006541	biological_process	glutamine metabolic process
I	0006542	biological_process	glutamine biosynthetic process
I	0016020	cellular_component	membrane
I	0016874	molecular_function	ligase activity
I	0019740	biological_process	nitrogen utilization
I	0030145	molecular_function	manganese ion binding
I	0046872	molecular_function	metal ion binding
I	0051260	biological_process	protein homooligomerization
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0004356	molecular_function	glutamine synthetase activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0006541	biological_process	glutamine metabolic process
J	0006542	biological_process	glutamine biosynthetic process
J	0016020	cellular_component	membrane
J	0016874	molecular_function	ligase activity
J	0019740	biological_process	nitrogen utilization
J	0030145	molecular_function	manganese ion binding
J	0046872	molecular_function	metal ion binding
J	0051260	biological_process	protein homooligomerization
K	0000166	molecular_function	nucleotide binding
K	0003824	molecular_function	catalytic activity
K	0004356	molecular_function	glutamine synthetase activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0006541	biological_process	glutamine metabolic process
K	0006542	biological_process	glutamine biosynthetic process
K	0016020	cellular_component	membrane
K	0016874	molecular_function	ligase activity
K	0019740	biological_process	nitrogen utilization
K	0030145	molecular_function	manganese ion binding
K	0046872	molecular_function	metal ion binding
K	0051260	biological_process	protein homooligomerization
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0004356	molecular_function	glutamine synthetase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006541	biological_process	glutamine metabolic process
L	0006542	biological_process	glutamine biosynthetic process
L	0016020	cellular_component	membrane
L	0016874	molecular_function	ligase activity
L	0019740	biological_process	nitrogen utilization
L	0030145	molecular_function	manganese ion binding
L	0046872	molecular_function	metal ion binding
L	0051260	biological_process	protein homooligomerization

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 469

Chain	Residue
A	GLU131
A	GLU212
A	GLU220
A	ADP1471
A	HOH1550
A	HOH1583

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 470

Chain	Residue
A	HOH1582
B	HOH1490
A	GLU129
A	HIS269
A	GLU357

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 469

Chain	Residue
B	GLU131
B	GLU212
B	GLU220
B	ADP1472
B	HOH1558
B	HOH1590

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 470

Chain	Residue
B	GLU129
B	HIS269
B	GLU357
B	HOH1589
C	HOH1492

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN C 469

Chain	Residue
C	GLU131
C	GLU212
C	GLU220
C	ADP1473
C	HOH1560
D	HOH1494

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 470

Chain	Residue
C	GLU129
C	HIS269
C	GLU357
C	HOH1590
D	HOH1493

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN D 469

Chain	Residue
D	GLU131
D	GLU212
D	GLU220
D	ADP1474
D	HOH1562
D	HOH1595

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 470

Chain	Residue
D	GLU129
D	HIS269
D	GLU357
D	HOH1594
E	HOH1493

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 469

Chain	Residue
E	GLU131
E	GLU212
E	GLU220
E	ADP1475
E	HOH1560
E	HOH1592

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN E 470

Chain	Residue
E	GLU129
E	HIS269
E	GLU357
E	HOH1591
F	HOH1496

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN F 469

Chain	Residue
F	GLU131
F	GLU212
F	GLU220
F	ADP1476
F	HOH1565
F	HOH1597

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN F 470

Chain	Residue
A	HOH1596
F	GLU129
F	HIS269
F	GLU357
F	HOH1596

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN G 469

Chain	Residue
G	GLU131
G	GLU212
G	GLU220
G	ADP1477
G	HOH1565
G	HOH1597

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN G 470

Chain	Residue
G	GLU129
G	HIS269
G	GLU357
G	HOH1596
L	HOH838

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN H 469

Chain	Residue
H	GLU131
H	GLU212
H	GLU220
H	ADP1478
H	HOH1565
H	HOH1597

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN H 470

Chain	Residue
G	HOH1609
H	GLU129
H	HIS269
H	GLU357
H	HOH1596

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN I 469

Chain	Residue
I	GLU131
I	GLU212
I	GLU220
I	ADP1479
I	HOH1567
I	HOH1599

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN I 470

Chain	Residue
H	HOH1611
I	GLU129
I	HIS269
I	GLU357
I	HOH1598

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN J 469

Chain	Residue
J	GLU131
J	GLU212
J	GLU220
J	ADP1480
J	HOH1567
J	HOH1598

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN J 470

Chain	Residue
I	HOH1613
J	GLU129
J	HIS269
J	GLU357
J	HOH1597

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN K 469

Chain	Residue
K	GLU131
K	GLU212
K	GLU220
K	ADP1481
K	HOH1570
K	HOH1602

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN K 470

Chain	Residue
J	HOH1612
K	GLU129
K	HIS269
K	GLU357
K	HOH1601

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN L 469

Chain	Residue
L	GLU131
L	GLU212
L	GLU220
L	HOH1406
L	HOH1445
L	ADP1482

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN L 470

Chain	Residue
K	HOH1616
L	GLU129
L	HIS269
L	GLU357
L	HOH1444

site_id	CC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP A 1471

Chain	Residue
A	GLU129
A	GLU207
A	HIS210
A	GLU220
A	THR223
A	PHE225
A	HIS271
A	SER273
A	ARG355
A	MN469
A	HOH1487
A	HOH1550
A	HOH1583
B	ASP50

site_id	CC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP B 1472

Chain	Residue
B	GLU129
B	GLU207
B	HIS210
B	GLU220
B	THR223
B	PHE225
B	HIS271
B	SER273
B	ARG355
B	MN469
B	HOH1494
B	HOH1558
B	HOH1590
C	ASP50

site_id	CC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP C 1473

Chain	Residue
C	GLU129
C	GLU207
C	HIS210
C	GLU220
C	THR223
C	PHE225
C	HIS271
C	SER273
C	ARG355
C	MN469
C	HOH1496
C	HOH1560
D	ASP50
D	HOH1494

site_id	DC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP D 1474

Chain	Residue
D	GLU129
D	GLU207
D	HIS210
D	GLU220
D	THR223
D	PHE225
D	HIS271
D	SER273
D	ARG355
D	MN469
D	HOH1498
D	HOH1562
D	HOH1595
E	ASP50

site_id	DC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP E 1475

Chain	Residue
E	GLU129
E	GLU207
E	HIS210
E	GLU220
E	THR223
E	PHE225
E	HIS271
E	SER273
E	ARG355
E	MN469
E	HOH1497
E	HOH1560
E	HOH1592
F	ASP50

site_id	DC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP F 1476

Chain	Residue
A	ASP50
F	GLU129
F	GLU207
F	HIS210
F	GLU220
F	THR223
F	PHE225
F	HIS271
F	SER273
F	ARG355
F	MN469
F	HOH1500
F	HOH1565
F	HOH1597

site_id	DC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP G 1477

Chain	Residue
G	GLU129
G	GLU207
G	HIS210
G	GLU220
G	THR223
G	PHE225
G	HIS271
G	SER273
G	ARG355
G	MN469
G	HOH1501
G	HOH1565
G	HOH1597
L	ASP50

site_id	DC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP H 1478

Chain	Residue
G	ASP50
H	GLU129
H	GLU207
H	HIS210
H	GLU220
H	THR223
H	PHE225
H	HIS271
H	SER273
H	ARG355
H	MN469
H	HOH1500
H	HOH1565
H	HOH1597

site_id	DC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP I 1479

Chain	Residue
H	ASP50
I	GLU129
I	GLU207
I	HIS210
I	GLU220
I	THR223
I	PHE225
I	HIS271
I	SER273
I	ARG355
I	MN469
I	HOH1503
I	HOH1567
I	HOH1599

site_id	DC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP J 1480

Chain	Residue
I	ASP50
J	GLU129
J	GLU207
J	HIS210
J	GLU220
J	THR223
J	PHE225
J	HIS271
J	SER273
J	ARG355
J	MN469
J	HOH1503
J	HOH1567
J	HOH1598

site_id	DC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP K 1481

Chain	Residue
J	ASP50
K	GLU129
K	GLU207
K	HIS210
K	GLU220
K	THR223
K	PHE225
K	HIS271
K	SER273
K	ARG355
K	MN469
K	HOH1507
K	HOH1570
K	HOH1602

site_id	DC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP L 1482

Chain	Residue
K	ASP50
L	GLU129
L	GLU207
L	HIS210
L	GLU220
L	THR223
L	PHE225
L	HIS271
L	SER273
L	ARG355
L	MN469
L	HOH1336
L	HOH1406
L	HOH1445

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL A 473

Chain	Residue
A	TYR179
A	GLU212
B	ASP50
B	SER53

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL A 474

Chain	Residue
A	GLU131
A	ASN264
A	GLY265
A	HOH1584

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL B 473

Chain	Residue
B	TYR179
B	GLU212
C	ASP50
C	SER53

site_id	EC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL B 474

Chain	Residue
B	GLU131
B	ASN264
B	GLY265
B	HOH1591

site_id	EC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL C 473

Chain	Residue
C	TYR179
C	GLU212
D	ASP50
D	SER53

site_id	EC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL C 474

Chain	Residue
C	GLU131
C	ASN264
C	GLY265
C	HOH1591

site_id	EC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL D 473

Chain	Residue
D	TYR179
D	GLU212
E	ASP50
E	SER53

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL D 474

Chain	Residue
D	GLU131
D	ASN264
D	GLY265
D	HOH1596

site_id	EC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL E 473

Chain	Residue
E	TYR179
E	GLU212
F	ASP50
F	SER53

site_id	FC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL E 474

Chain	Residue
E	GLU131
E	ASN264
E	GLY265
E	HOH1593

site_id	FC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL F 473

Chain	Residue
A	ASP50
A	SER53
F	TYR179
F	GLU212

site_id	FC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL F 474

Chain	Residue
F	GLU131
F	ASN264
F	GLY265
F	HOH1598

site_id	FC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL G 473

Chain	Residue
G	TYR179
G	GLU212
L	ASP50
L	SER53

site_id	FC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL G 474

Chain	Residue
G	GLU131
G	ASN264
G	GLY265
G	HOH1598

site_id	FC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL H 473

Chain	Residue
G	ASP50
G	SER53
H	TYR179
H	GLU212

site_id	FC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL H 474

Chain	Residue
H	GLU131
H	ASN264
H	GLY265
H	HOH1598

site_id	FC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL I 473

Chain	Residue
H	ASP50
H	SER53
I	TYR179
I	GLU212

site_id	FC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL I 474

Chain	Residue
I	GLU131
I	ASN264
I	GLY265
I	HOH1600

site_id	GC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL J 473

Chain	Residue
I	ASP50
I	SER53
J	TYR179
J	GLU212

site_id	GC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL J 474

Chain	Residue
J	GLU131
J	ASN264
J	GLY265
J	HOH1599

site_id	GC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL K 473

Chain	Residue
J	ASP50
J	SER53
K	TYR179
K	GLU212

site_id	GC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL K 474

Chain	Residue
K	GLU131
K	ASN264
K	GLY265
K	HOH1603

site_id	GC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL L 473

Chain	Residue
K	ASP50
K	SER53
L	TYR179
L	GLU212

site_id	GC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TL L 474

Chain	Residue
L	GLU131
L	ASN264
L	GLY265
L	HOH1446

site_id	GC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD A 1483

Chain	Residue
A	PHE16
A	PHE80
A	ALA81
A	ASP82
A	THR84
F	GLN189
F	ASP190
F	SER193

site_id	GC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD B 1484

Chain	Residue
A	GLN189
A	ASP190
A	SER193
B	PHE16
B	PHE80
B	ALA81
B	ASP82
B	THR84

site_id	GC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD C 1485

Chain	Residue
B	GLN189
B	ASP190
B	SER193
C	PHE16
C	PHE80
C	ALA81
C	ASP82
C	THR84

site_id	HC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD D 1486

Chain	Residue
C	GLN189
C	ASP190
C	SER193
D	PHE16
D	PHE80
D	ALA81
D	ASP82
D	THR84

site_id	HC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD E 1487

Chain	Residue
D	GLN189
D	ASP190
D	SER193
E	PHE16
E	PHE80
E	ALA81
E	ASP82
E	THR84

site_id	HC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD F 1488

Chain	Residue
E	GLN189
E	ASP190
E	SER193
F	PHE16
F	PHE80
F	ALA81
F	ASP82
F	THR84

site_id	HC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD G 1489

Chain	Residue
G	PHE16
G	PHE80
G	ALA81
G	ASP82
G	THR84
H	GLN189
H	ASP190
H	SER193

site_id	HC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD H 1490

Chain	Residue
H	PHE16
H	PHE80
H	ALA81
H	ASP82
H	THR84
H	HOH1606
I	GLN189
I	ASP190
I	SER193

site_id	HC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD I 1491

Chain	Residue
I	PHE16
I	PHE80
I	ALA81
I	ASP82
I	THR84
J	GLN189
J	ASP190
J	SER193

site_id	HC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD J 1492

Chain	Residue
J	PHE16
J	PHE80
J	ALA81
J	ASP82
J	THR84
K	GLN189
K	ASP190
K	SER193

site_id	HC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD K 1493

Chain	Residue
K	PHE16
K	PHE80
K	ALA81
K	ASP82
K	THR84
L	GLN189
L	ASP190
L	SER193

site_id	HC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD L 1494

Chain	Residue
G	GLN189
G	ASP190
G	SER193
L	PHE16
L	PHE80
L	ALA81
L	ASP82
L	THR84
L	HOH733

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiggwkginESDmvL

Chain	Residue	Details
A	PHE49-LEU67

site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPMfgd..NGSGmHchmS

Chain	Residue	Details
A	LYS258-SER273

site_id	PS00182
Number of Residues	13
Details	GLNA_ADENYLATION Glutamine synthetase class-I adenylation site. KIhpgepMDKNLY

Chain	Residue	Details
A	LYS385-TYR397

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1008
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4368
Details	Domain: {"description":"GS catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01331","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2572586","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GLS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12425","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P77961","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2572586","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GLS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	12
Details	Modified residue: {"description":"O-AMP-tyrosine","evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
A	ARG339
A	ASP50
A	GLU327

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
J	ARG339
J	ASP50
J	GLU327

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
K	ARG339
K	ASP50
K	GLU327

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
L	ARG339
L	ASP50
L	GLU327

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
B	ARG339
B	ASP50
B	GLU327

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
C	ARG339
C	ASP50
C	GLU327

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
D	ARG339
D	ASP50
D	GLU327

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
E	ARG339
E	ASP50
E	GLU327

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
F	ARG339
F	ASP50
F	GLU327

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
G	ARG339
G	ASP50
G	GLU327

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
H	ARG339
H	ASP50
H	GLU327

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
I	ARG339
I	ASP50
I	GLU327

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)