1EYF

REFINED STRUCTURE OF THE DNA METHYL PHOSPHOTRIESTER REPAIR DOMAIN OF E. COLI ADA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006281	biological_process	DNA repair
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008168	molecular_function	methyltransferase activity
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 93

Chain	Residue
A	CYS38
A	CYS42
A	CYS69
A	CYS72

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile; methyl group acceptor from methylphosphotriester => ECO:0000255|PROSITE-ProRule:PRU10017, ECO:0000269|PubMed:16452614

Chain	Residue	Details
A	CYS38

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16209950

Chain	Residue	Details
A	THR34
A	ARG43
A	ARG45
A	ARG67

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	CYS38
A	CYS42
A	CYS69
A	CYS72

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 295

Chain	Residue	Details
A	CYS38	activator, attractive charge-charge interaction, metal ligand, nucleophile
A	CYS42	metal ligand
A	CYS69	metal ligand
A	CYS72	metal ligand

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