Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005031 | molecular_function | tumor necrosis factor receptor activity |
| A | 0006693 | biological_process | prostaglandin metabolic process |
| A | 0006954 | biological_process | inflammatory response |
| A | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| B | 0005031 | molecular_function | tumor necrosis factor receptor activity |
| B | 0006693 | biological_process | prostaglandin metabolic process |
| B | 0006954 | biological_process | inflammatory response |
| B | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | PRO23 |
| A | ARG68 |
| A | ARG99 |
| A | HOH421 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | ARG68 |
| A | ARG99 |
| A | LYS100 |
| A | HOH480 |
| B | HOH325 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | TYR103 |
| A | GLN133 |
| A | ASN134 |
| A | HOH450 |
| A | HOH466 |
| A | HOH476 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 404 |
| Chain | Residue |
| A | GLU147 |
| A | HOH473 |
| A | HOH497 |
| B | HOH219 |
| B | HOH257 |
| B | HOH275 |
Functional Information from PROSITE/UniProt
| site_id | PS00652 |
| Number of Residues | 38 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. CpqgkyiHpqnnsi....C..Ctk.Chkgtylynd..Cpgpgq.DTDC |
| Chain | Residue | Details |
| A | CYS15-CYS52 | |
| A | CYS55-CYS96 | |
| A | CYS96-CYS137 | |
| site_id | PS01186 |
| Number of Residues | 14 |
| Details | EGF_2 EGF-like domain signature 2. CtChaGFflrene..C |
| Chain | Residue | Details |
| A | CYS137-CYS150 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"TNFR-Cys 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"TNFR-Cys 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 58 |
| Details | Repeat: {"description":"TNFR-Cys 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
