1ERR
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE RAL A 600 |
| Chain | Residue |
| A | HOH3 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | ILE424 |
| A | HIS524 |
| A | LEU525 |
| A | LEU536 |
| A | LEU346 |
| A | THR347 |
| A | ALA350 |
| A | ASP351 |
| A | GLU353 |
| A | LEU354 |
| A | TRP383 |
| A | LEU387 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE RAL B 600 |
| Chain | Residue |
| B | HOH61 |
| B | LEU346 |
| B | THR347 |
| B | ALA350 |
| B | ASP351 |
| B | GLU353 |
| B | TRP383 |
| B | LEU391 |
| B | ARG394 |
| B | ILE424 |
| B | HIS524 |
| B | LEU536 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| A | TYR537 | |
| B | TYR537 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 |
