1ERE
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EST A 600 |
| Chain | Residue |
| A | HOH3 |
| A | LEU346 |
| A | GLU353 |
| A | LEU387 |
| A | LEU391 |
| A | ARG394 |
| A | HIS524 |
| A | LEU525 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EST B 600 |
| Chain | Residue |
| B | LEU346 |
| B | GLU353 |
| B | ARG394 |
| B | HIS524 |
| B | LEU525 |
| B | HOH22 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EST C 600 |
| Chain | Residue |
| C | HOH41 |
| C | LEU346 |
| C | GLU353 |
| C | LEU391 |
| C | ARG394 |
| C | HIS524 |
| C | LEU525 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EST D 600 |
| Chain | Residue |
| D | HOH60 |
| D | LEU346 |
| D | GLU353 |
| D | ARG394 |
| D | HIS524 |
| D | LEU525 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EST E 600 |
| Chain | Residue |
| E | HOH79 |
| E | LEU346 |
| E | GLU353 |
| E | ARG394 |
| E | HIS524 |
| E | LEU525 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EST F 600 |
| Chain | Residue |
| F | HOH98 |
| F | GLU353 |
| F | LEU387 |
| F | LEU391 |
| F | ARG394 |
| F | HIS524 |
| F | LEU525 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9338790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9600906","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ERE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphotyrosine; by Tyr-kinases","evidences":[{"source":"PubMed","id":"7539106","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
