1ERA

TERTIARY STRUCTURE OF ERABUTOXIN B IN AQUEOUS SOLUTION ELUCIDATED BY TWO-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0030550	molecular_function	acetylcholine receptor inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PROSITE/UniProt

site_id	PS00272
Number of Residues	19
Details	SNAKE_TOXIN Snake toxins signature. GCg..CPtvkpgikls.CCesE

Chain	Residue	Details
A	GLY40-GLU58

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	SITE: Moderately important residue for binding to acetylcholine receptor => ECO:0000250|UniProtKB:P60775

Chain	Residue	Details
A	HIS6
A	SER9
A	TYR25
A	PHE32
A	GLY34

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site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Very important residue for binding to acetylcholine receptor => ECO:0000250|UniProtKB:P60775

Chain	Residue	Details
A	GLN7
A	TRP29
A	ASP31
A	ILE36
A	GLU38
A	LYS47

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Key residue for binding to acetylcholine receptor => ECO:0000250|UniProtKB:P60775

Chain	Residue	Details
A	SER8
A	GLN10
A	LYS27
A	ARG33

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