1EP5

CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004252	molecular_function	serine-type endopeptidase activity
B	0006508	biological_process	proteolysis
C	0004252	molecular_function	serine-type endopeptidase activity
C	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 759

Chain	Residue
A	LYS135
A	GLY144
A	ARG185

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 859

Chain	Residue
A	PRO181
A	GLN182
A	LYS218
A	GLY219
A	HOH968

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE URE B 940

Chain	Residue
B	GLN197

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE B 941

Chain	Residue
B	THR192
B	HIS193
B	HOH984
B	HOH995

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE B 942

Chain	Residue
A	ALA206
B	TYR199
B	PRO217
B	ARG250
B	HOH952

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE URE A 943

Chain	Residue
A	THR264

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 944

Chain	Residue
A	THR192
A	HIS193
A	HOH1000

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE B 945

Chain	Residue
A	TYR199
A	ARG250
B	ALA206
B	HOH966

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE B 946

Chain	Residue
B	HIS203
B	HIS204

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	ACT_SITE: Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01027

Chain	Residue	Details
B	HIS152
B	ASP174
B	SER226
A	HIS152
A	ASP174
A	SER226
C	HIS152
C	ASP174
C	SER226

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Involved in dimerization of the capsid protein => ECO:0000250|UniProtKB:Q86925

Chain	Residue	Details
B	TYR200
B	ASN233
A	TYR200
A	ASN233
C	TYR200
C	ASN233

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	SITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:P03315

Chain	Residue	Details
B	TRP275
A	TRP275
C	TRP275

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P09592

Chain	Residue	Details
B	SER124
A	SER124
C	SER124

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P09592

Chain	Residue	Details
B	THR127
A	THR127
C	THR127

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