1EO7

BACILLUS CIRCULANS STRAIN 251 CYCLODEXTRIN GLYCOSYLTRANSFERASE IN COMPLEX WITH MALTOHEXAOSE

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Functional Information from GO Data

ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0043895molecular_functioncyclomaltodextrin glucanotransferase activity
A0046872molecular_functionmetal ion binding
A2001070molecular_functionstarch binding
A0005975biological_processcarbohydrate metabolic process
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC111BINDING SITE FOR RESIDUE GLC A 691
ChainResidue
ATYR100
AHIS140
ALEU194
ALEU197
AARG227
AALA229
AALA230
AHIS327
AASP328
AARG375
AGLC692

AC28BINDING SITE FOR RESIDUE GLC A 692
ChainResidue
AHIS98
ATYR100
ATRP101
AASP371
AARG375
AGLC691
AGLC693
AHOH806

AC36BINDING SITE FOR RESIDUE GLC A 693
ChainResidue
ATYR89
AASP371
AGLC692
AGLC694
AHOH806
AHOH843

AC43BINDING SITE FOR RESIDUE GLC A 694
ChainResidue
ATYR195
AGLC693
AGLC695

AC55BINDING SITE FOR RESIDUE GLC A 695
ChainResidue
AGLY180
ATYR195
AGLC694
AGLC696
AHOH853

AC68BINDING SITE FOR RESIDUE GLC A 696
ChainResidue
AALA144
ASER145
AGLY180
AASN193
ATYR195
AASP196
AASN457
AGLC695

AC74BINDING SITE FOR RESIDUE GLC A 698
ChainResidue
AARG339
ASER384
AGLC699
AHOH784

AC86BINDING SITE FOR RESIDUE GLC A 699
ChainResidue
ALYS651
ATRP662
AGLU663
AGLC698
AGLC700
AHOH807

AC93BINDING SITE FOR RESIDUE GLC A 700
ChainResidue
ATRP616
AASN667
AGLC699

BC12BINDING SITE FOR RESIDUE GLC A 702
ChainResidue
ALEU600
AGLC703

BC25BINDING SITE FOR RESIDUE GLC A 703
ChainResidue
ATHR598
AALA599
ALEU600
AGLC702
AGLC704

BC39BINDING SITE FOR RESIDUE GLC A 704
ChainResidue
AALA599
ALEU600
AGLY601
AGLN602
AASN603
AASN627
AGLN628
AGLC703
AGLC705

BC42BINDING SITE FOR RESIDUE GLC A 705
ChainResidue
AASN603
AGLC704

BC57BINDING SITE FOR RESIDUE GLC A 707
ChainResidue
ATRP413
AILE414
ASER445
AGLY446
AALA539
AASP540
AGLC708

BC66BINDING SITE FOR RESIDUE GLC A 708
ChainResidue
AGLU411
AARG412
AGLY446
AVAL448
AGLC707
AGLC709

BC71BINDING SITE FOR RESIDUE GLC A 709
ChainResidue
AGLC708

BC87BINDING SITE FOR RESIDUE CA A 688
ChainResidue
AASP27
AASN29
AASN32
AASN33
AGLY51
AASP53
AHOH757

BC96BINDING SITE FOR RESIDUE CA A 689
ChainResidue
AASN139
AILE190
AASP199
AHIS233
AHOH749
AHOH753

CC13BINDING SITE FOR RESIDUE CA A 690
ChainResidue
AALA315
AASP577
AHOH856

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
GLC_1eo7_A_69212ALPHA-D-GLUCOSE binding site
ChainResidueligand
APHE21GLC: ALPHA-D-GLUCOSE
ATYR97-HIS98GLC: ALPHA-D-GLUCOSE
ATYR100-TRP101GLC: ALPHA-D-GLUCOSE
ATYR195-LEU197GLC: ALPHA-D-GLUCOSE
AHIS327-ASP328GLC: ALPHA-D-GLUCOSE
AASP371GLC: ALPHA-D-GLUCOSE
AARG375GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_6936ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATYR89GLC: ALPHA-D-GLUCOSE
AASN94GLC: ALPHA-D-GLUCOSE
ATRP101GLC: ALPHA-D-GLUCOSE
ATYR195-ASP196GLC: ALPHA-D-GLUCOSE
AASP371GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_6943ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATYR89GLC: ALPHA-D-GLUCOSE
ATYR195-ASP196GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_69113ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATYR100GLC: ALPHA-D-GLUCOSE
AASP135GLC: ALPHA-D-GLUCOSE
AALA137GLC: ALPHA-D-GLUCOSE
AHIS140GLC: ALPHA-D-GLUCOSE
ALEU194GLC: ALPHA-D-GLUCOSE
ALEU197GLC: ALPHA-D-GLUCOSE
AARG227GLC: ALPHA-D-GLUCOSE
AALA229-ALA230GLC: ALPHA-D-GLUCOSE
AALA257GLC: ALPHA-D-GLUCOSE
AHIS327-ASP328GLC: ALPHA-D-GLUCOSE
AARG375GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_6969ALPHA-D-GLUCOSE binding site
ChainResidueligand
AALA144-SER145GLC: ALPHA-D-GLUCOSE
ATYR167GLC: ALPHA-D-GLUCOSE
AGLY179-GLY180GLC: ALPHA-D-GLUCOSE
AASN193GLC: ALPHA-D-GLUCOSE
ATYR195-LEU197GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_6955ALPHA-D-GLUCOSE binding site
ChainResidueligand
AGLY180-THR181GLC: ALPHA-D-GLUCOSE
AASN193GLC: ALPHA-D-GLUCOSE
ATYR195-ASP196GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7054ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATHR185GLC: ALPHA-D-GLUCOSE
AGLY601GLC: ALPHA-D-GLUCOSE
AASN603GLC: ALPHA-D-GLUCOSE
AGLN628GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7087ALPHA-D-GLUCOSE binding site
ChainResidueligand
AGLU411-ILE414GLC: ALPHA-D-GLUCOSE
AGLY446-VAL448GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7078ALPHA-D-GLUCOSE binding site
ChainResidueligand
AGLU411-ASN415GLC: ALPHA-D-GLUCOSE
ASER445-LEU447GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7036ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATHR598-LEU600GLC: ALPHA-D-GLUCOSE
AGLN602GLC: ALPHA-D-GLUCOSE
AASN627GLC: ALPHA-D-GLUCOSE
ATYR633GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7049ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATHR598-ASN603GLC: ALPHA-D-GLUCOSE
AASN627-GLN628GLC: ALPHA-D-GLUCOSE
ATRP636GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7021ALPHA-D-GLUCOSE binding site
ChainResidueligand
ALEU600GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_7005ALPHA-D-GLUCOSE binding site
ChainResidueligand
ATRP616GLC: ALPHA-D-GLUCOSE
AGLU649GLC: ALPHA-D-GLUCOSE
ALYS651GLC: ALPHA-D-GLUCOSE
ATRP662GLC: ALPHA-D-GLUCOSE
AASN667GLC: ALPHA-D-GLUCOSE

GLC_1eo7_A_6994ALPHA-D-GLUCOSE binding site
ChainResidueligand
ALYS651GLC: ALPHA-D-GLUCOSE
ATRP662-GLU663GLC: ALPHA-D-GLUCOSE
AASN667GLC: ALPHA-D-GLUCOSE

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI11Proton donor.
ChainResidueDetails
AALA257

SWS_FT_FI21Nucleophile.
ChainResidueDetails
AALA229

SWS_FT_FI32Calcium 1; via carbonyl oxygen
ChainResidueDetails
AASN29
AGLY51

SWS_FT_FI41Calcium 3
ChainResidueDetails
AASP577

SWS_FT_FI52Calcium 2
ChainResidueDetails
AASN139
AASP199

SWS_FT_FI62Calcium 2; via carbonyl oxygen
ChainResidueDetails
AILE190
AHIS233

SWS_FT_FI74Calcium 1
ChainResidueDetails
AASP27
AASN32
AASN33
AASP53

SWS_FT_FI81Calcium 3; via carbonyl oxygen
ChainResidueDetails
AALA315

SWS_FT_FI95Substrate.
ChainResidueDetails
AHIS140
AARG227
AHIS327
AASP371
AARG375

SWS_FT_FI101Transition state stabilizer (By similarity).
ChainResidueDetails
AASP328

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Catalytic Information from CSA

site_idNumber of ResiduesDetails