1EMO

NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 2224

Chain	Residue
A	ASP2127
A	MET2128
A	GLU2130
A	ASN2144
A	THR2145
A	SER2148

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 2225

Chain	Residue
A	ASP2166
A	THR2167
A	GLU2169
A	ASN2183
A	VAL2184
A	GLY2187

---

site_id	CA1
Number of Residues	6
Details	CALCIUM BINDING SITE FOR EGF-LIKE DOMAIN 32.

Chain	Residue
A	ASP2127
A	ASP2129
A	GLU2130
A	ASN2144
A	TYR2149
A	CA2224

---

site_id	CA2
Number of Residues	6
Details	CALCIUM BINDING SITE FOR EGF-LIKE DOMAIN 33.

Chain	Residue
A	ASN2183
A	PHE2188
A	CA2225
A	ASP2166
A	ASP2168
A	GLU2169

---

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CiNtdgsYrCeC

Chain	Residue	Details
A	CYS2142-CYS2153
A	CYS2181-CYS2192

---

site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CeCpfGYilagne..C

Chain	Residue	Details
A	CYS2151-CYS2164
A	CYS2190-CYS2204

---

site_id	PS01187
Number of Residues	25
Details	EGF_CA Calcium-binding EGF-like domain signature. DmDECkepdv.........Ckhgq...CiNtdgsYrC

Chain	Residue	Details
A	ASP2127-CYS2151
A	ASP2166-CYS2190

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	Domain: {"description":"EGF-like 36; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	39
Details	Domain: {"description":"EGF-like 37; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (Glc) serine","evidences":[{"source":"PubMed","id":"34411563","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---