1ELM

CADMIUM-SUBSTITUTED BOVINE PACREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 5.5 AND 2 MM CHLORIDE IN MONOCLINIC CRYSTAL FORM.

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0004181	molecular_function	metallocarboxypeptidase activity
P	0006508	biological_process	proteolysis
P	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD P 350

Chain	Residue
P	HIS69
P	GLU72
P	HIS196
P	HOH401
P	HOH550

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD P 351

Chain	Residue
P	HIS303

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Functional Information from PROSITE/UniProt

site_id	PS00132
Number of Residues	23
Details	CARBOXYPEPT_ZN_1 Zinc carboxypeptidases, zinc-binding region 1 signature. PaIwIdlGiHSrEwITQatgvwF

Chain	Residue	Details
P	PRO60-PHE82

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site_id	PS00133
Number of Residues	11
Details	CARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HSYSQLLlYPY

Chain	Residue	Details
P	HIS196-TYR206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|PROSITE-ProRule:PRU01379

Chain	Residue	Details
P	GLU270

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01379, ECO:0000269|PubMed:12431056, ECO:0007744|PDB:1IY7

Chain	Residue	Details
P	HIS69
P	GLU72
P	HIS196

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:12431056, ECO:0007744|PDB:1IY7

Chain	Residue	Details
P	ARG127
P	ASN144
P	SER197
P	TYR248

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1cbx

Chain	Residue	Details
P	ARG127
P	GLU270

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site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1cbx

Chain	Residue	Details
P	ARG71
P	GLU270
P	ARG127

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site_id	MCSA1
Number of Residues	5
Details	M-CSA 171

Chain

Residue

Details

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