Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006413 | biological_process | translational initiation |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003743 | molecular_function | translation initiation factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006413 | biological_process | translational initiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE M7G A 1000 |
| Chain | Residue |
| A | TRP56 |
| A | HOH1005 |
| A | HOH1007 |
| A | HOH1008 |
| A | HOH1018 |
| A | MET101 |
| A | TRP102 |
| A | GLU103 |
| A | ARG157 |
| A | LYS162 |
| A | HOH1002 |
| A | HOH1003 |
| A | HOH1004 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE M7G B 1001 |
| Chain | Residue |
| B | TRP56 |
| B | MET101 |
| B | TRP102 |
| B | GLU103 |
| B | ARG157 |
| B | LYS162 |
| B | HOH1007 |
| B | HOH1008 |
| B | HOH1041 |
| B | HOH1049 |
Functional Information from PROSITE/UniProt
| site_id | PS00813 |
| Number of Residues | 24 |
| Details | IF4E Eukaryotic initiation factor 4E signature. DYslFKdgIePmWEDeknkrGGRW |
| Chain | Residue | Details |
| A | ASP90-TRP113 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Region: {"description":"EIF4EBP1/2/3 binding","evidences":[{"source":"PubMed","id":"10394359","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10394359","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9200613","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC and MKNK2","evidences":[{"source":"PubMed","id":"17689282","evidenceCode":"ECO:0000269"}]} |
