1EHA

CRYSTAL STRUCTURE OF GLYCOSYLTREHALOSE TREHALOHYDROLASE FROM SULFOLOBUS SOLFATARICUS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0005992	biological_process	trehalose biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0033942	molecular_function	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000305|PubMed:22334583

Chain	Residue	Details
A	ALA253

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:22334583

Chain	Residue	Details
A	SER284

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:22334583

Chain	Residue	Details
A	LEU251
A	ASP309
A	ASP377

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site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Transition state stabilizer => ECO:0000305|PubMed:22334583

Chain	Residue	Details
A	GLN378

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASN277
A	ASP252

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site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASN381
A	GLN305
A	ASP252

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASP303
A	ASP252

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site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASP285
A	ASP252

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site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	GLN305
A	ASP252

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site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	HIS192
A	ASP377
A	GLU283
A	ASP252

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site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASP377
A	GLU283
A	ASP252

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