Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| E | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE 0Q4 D 201 |
| Chain | Residue |
| C | ASP25 |
| D | LEU123 |
| D | ASP125 |
| D | GLY127 |
| D | ALA128 |
| D | ASP129 |
| D | ASP130 |
| D | MET146 |
| D | ILE147 |
| D | GLY148 |
| D | GLY149 |
| C | GLY27 |
| D | PRO181 |
| D | VAL182 |
| D | ILE184 |
| D | HOH1435 |
| D | HOH1447 |
| E | TRP6 |
| C | ALA28 |
| C | ASP29 |
| C | ASP30 |
| C | GLY48 |
| C | GLY49 |
| C | ILE50 |
| C | ILE84 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE 0Q4 E 501 |
| Chain | Residue |
| E | ASP25 |
| E | GLY27 |
| E | ALA28 |
| E | ASP29 |
| E | ASP30 |
| E | THR31 |
| E | VAL32 |
| E | LYS45 |
| E | ILE47 |
| E | GLY48 |
| E | GLY49 |
| E | ILE50 |
| E | HOH1320 |
| E | HOH1343 |
| F | LEU123 |
| F | ASP125 |
| F | GLY127 |
| F | ALA128 |
| F | ASP129 |
| F | LYS145 |
| F | ILE147 |
| F | GLY148 |
| F | GLY149 |
| F | VAL182 |
| F | ILE184 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| C | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 276 |
| Details | Domain: {"description":"Peptidase A2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00275","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12924029","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| D | THR126 | |
| D | ASP125 | |
| C | ASP25 | |
| C | THR26 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| F | THR126 | |
| F | ASP125 | |
| E | ASP25 | |
| E | THR26 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| C | ASP25 | |
| D | ASP125 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| F | ASP125 | |
| E | ASP25 | |
