1E9V

XENON BOUND IN HYDROPHOBIC CHANNEL OF HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO VULGARIS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004601	molecular_function	peroxidase activity
A	0005737	cellular_component	cytoplasm
A	0016491	molecular_function	oxidoreductase activity
A	0016661	molecular_function	oxidoreductase activity, acting on other nitrogenous compounds as donors
A	0042542	biological_process	response to hydrogen peroxide
A	0046872	molecular_function	metal ion binding
A	0050418	molecular_function	hydroxylamine reductase activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FSO A 600

Chain	Residue
A	HIS244
A	GLU268
A	ASN311
A	CYS312
A	CSS406
A	CYS434
A	CYS459
A	GLU494
A	LYS496

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SF4 A 650

Chain	Residue
A	CYS3
A	PHE4
A	GLN5
A	CYS6
A	THR9
A	CYS15
A	GLY19
A	MET20
A	CYS21
A	LYS23
A	THR71

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE XE A 703

Chain	Residue
A	LEU384
A	VAL388

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE XE A 705

Chain	Residue
A	LEU501

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE XE A 706

Chain	Residue
A	PHE400

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE XE A 707

Chain	Residue
A	LEU430

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE XE A 709

Chain	Residue
A	ILE490
A	ALA497

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE XE A 710

Chain	Residue
A	ILE481
A	TYR488
A	LEU504
A	VAL509

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE XE A 711

Chain	Residue
A	TRP492
A	LEU501

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE XE A 712

Chain	Residue
A	SER462

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 800

Chain	Residue
A	ASP76
A	TYR334
A	GLY336
A	ALA337
A	HOH2163
A	HOH2619

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE TRS A 803

Chain	Residue
A	THR227
A	ASN273
A	LYS279
A	PHE284
A	HOH2498
A	HOH2503
A	HOH2748

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACY A 801

Chain	Residue
A	GLU81
A	SER124
A	THR125

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 802

Chain	Residue
A	GLU181
A	LYS201
A	HOH2746
A	HOH2747

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11106482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12764602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18560155","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2000","submissionDatabase":"PDB data bank","title":"Ferricyanide soaked hybrid cluster protein at 1.2A and xenon mapping of the hydrophobic cavity at 1.8A.","authors":["Cooper S.J.","Garner C.D.","Hagen W.R.","Lindley P.F.","Bailey S."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"1998","firstPage":"81","lastPage":"95","volume":"3","journal":"J. Biol. Inorg. Chem.","title":"The 'prismane' protein resolved: X-ray structure at 1.7-A and multiple spectroscopy of two novel 4Fe clusters.","authors":["Arendsen A.F.","Hadden J.","Card G.","McAlpine A.S.","Bailey S.","Zaitsev V.","Duke E.H.M.","Lindley P.F.","Kroeckel M.","Trautwein A.X.","Feiters M.C.","Charnock J.M.","Garner C.D.","Marritt S.J.","Thomson A.J.","Kooter I.M.","Johnson M.K.","van den Berg W.A.M.","van Dongen W.M.A.M.","Hagen W.R."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11106482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12764602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18560155","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2000","submissionDatabase":"PDB data bank","title":"Ferricyanide soaked hybrid cluster protein at 1.2A and xenon mapping of the hydrophobic cavity at 1.8A.","authors":["Cooper S.J.","Garner C.D.","Hagen W.R.","Lindley P.F.","Bailey S."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"description":"via persulfide group","evidences":[{"source":"PubMed","id":"11106482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12764602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18560155","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2000","submissionDatabase":"PDB data bank","title":"Ferricyanide soaked hybrid cluster protein at 1.2A and xenon mapping of the hydrophobic cavity at 1.8A.","authors":["Cooper S.J.","Garner C.D.","Hagen W.R.","Lindley P.F.","Bailey S."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Cysteine persulfide","evidences":[{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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