1E9J
SOLUTION STRUCTURE OF THE A-SUBUNIT OF HUMAN CHORIONIC GONADOTROPIN [INCLUDING A SINGLE GLCNAC RESIDUE AT ASN52 AND ASN78]
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005179 | molecular_function | hormone activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005796 | cellular_component | Golgi lumen |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0008284 | biological_process | positive regulation of cell population proliferation |
| A | 0009755 | biological_process | hormone-mediated signaling pathway |
| A | 0010469 | biological_process | regulation of signaling receptor activity |
| A | 0010893 | biological_process | positive regulation of steroid biosynthetic process |
| A | 0016913 | molecular_function | follicle-stimulating hormone activity |
| A | 0016914 | cellular_component | follicle-stimulating hormone complex |
| A | 0030335 | biological_process | positive regulation of cell migration |
| A | 0042699 | biological_process | follicle-stimulating hormone signaling pathway |
| A | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| A | 0061696 | cellular_component | pituitary gonadotropin complex |
Functional Information from PROSITE/UniProt
| site_id | PS00779 |
| Number of Residues | 13 |
| Details | GLYCO_HORMONE_ALPHA_1 Glycoprotein hormones alpha chain signature 1. CmGCCFSRAYPTP |
| Chain | Residue | Details |
| A | CYS28-PRO40 |
| site_id | PS00780 |
| Number of Residues | 14 |
| Details | GLYCO_HORMONE_ALPHA_2 Glycoprotein hormones alpha chain signature 2. NHTaChCsTCyyHK |
| Chain | Residue | Details |
| A | ASN78-LYS91 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000036","evidences":[{"source":"PubMed","id":"15662415","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24692546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MQW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000037","evidences":[{"source":"PubMed","id":"15662415","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24692546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MQW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
