Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 1001 |
| Chain | Residue |
| A | ASP115 |
| A | ASP120 |
| A | ASP152 |
| A | HOH2507 |
| A | HOH2523 |
| A | PO43002 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 1002 |
| Chain | Residue |
| A | HOH2510 |
| A | HOH2523 |
| A | PO43002 |
| A | ASP120 |
| A | HOH2508 |
| A | HOH2509 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MN A 1003 |
| Chain | Residue |
| A | LYS56 |
| A | GLU58 |
| A | HOH2511 |
| A | HOH2512 |
| A | HOH2513 |
| A | HOH2514 |
| A | HOH2515 |
| A | HOH2516 |
| A | HOH2517 |
| A | PO43001 |
| A | PO43002 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 1004 |
| Chain | Residue |
| A | ASP147 |
| A | ASP152 |
| A | HOH2518 |
| A | HOH2519 |
| A | PO43001 |
| A | PO43002 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PO4 A 3001 |
| Chain | Residue |
| A | LYS56 |
| A | GLU58 |
| A | ARG78 |
| A | ASP147 |
| A | TYR192 |
| A | LYS193 |
| A | MN1003 |
| A | MN1004 |
| A | HOH2514 |
| A | HOH2516 |
| A | HOH2517 |
| A | HOH2519 |
| A | HOH2520 |
| A | HOH2521 |
| A | PO43002 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PO4 A 3002 |
| Chain | Residue |
| A | LYS56 |
| A | GLU58 |
| A | TYR93 |
| A | ASP115 |
| A | ASP117 |
| A | ASP120 |
| A | ASP152 |
| A | LYS154 |
| A | MN1001 |
| A | MN1002 |
| A | MN1003 |
| A | MN1004 |
| A | HOH2508 |
| A | HOH2518 |
| A | HOH2522 |
| A | HOH2523 |
| A | PO43001 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MN B 1005 |
| Chain | Residue |
| B | ASP115 |
| B | ASP120 |
| B | ASP152 |
| B | MN1006 |
| B | MN1008 |
| B | HOH2488 |
| B | HOH2489 |
| B | PO43002 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 1006 |
| Chain | Residue |
| B | ASP120 |
| B | MN1005 |
| B | HOH2489 |
| B | HOH2490 |
| B | HOH2491 |
| B | HOH2492 |
| B | PO43002 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 1007 |
| Chain | Residue |
| B | GLU58 |
| B | HOH2493 |
| B | HOH2494 |
| B | HOH2495 |
| B | PO43001 |
| B | PO43002 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 1008 |
| Chain | Residue |
| B | ASP147 |
| B | ASP152 |
| B | MN1005 |
| B | HOH2496 |
| B | HOH2497 |
| B | PO43001 |
| B | PO43002 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PO4 B 3001 |
| Chain | Residue |
| B | HOH2496 |
| B | HOH2498 |
| B | HOH2499 |
| B | PO43002 |
| B | LYS56 |
| B | GLU58 |
| B | ARG78 |
| B | ASP147 |
| B | TYR192 |
| B | LYS193 |
| B | MN1007 |
| B | MN1008 |
| B | HOH2493 |
| B | HOH2495 |
| site_id | BC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PO4 B 3002 |
| Chain | Residue |
| B | LYS56 |
| B | GLU58 |
| B | TYR93 |
| B | ASP115 |
| B | ASP120 |
| B | ASP152 |
| B | LYS154 |
| B | MN1005 |
| B | MN1006 |
| B | MN1007 |
| B | MN1008 |
| B | HOH2489 |
| B | HOH2497 |
| B | HOH2500 |
| B | PO43001 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DNDPIDV |
| Chain | Residue | Details |
| A | ASP115-VAL121 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"1322842","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"15665377","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| A | ASP117 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| B | ASP117 | |
