Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 A1158 |
| Chain | Residue |
| A | HIS41 |
| A | HOH2181 |
| A | HOH2182 |
| A | HOH2183 |
| A | HOH2185 |
| A | ASP42 |
| A | HIS43 |
| A | ARG54 |
| A | GLU65 |
| A | LYS69 |
| A | HOH2074 |
| A | HOH2179 |
| A | HOH2180 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1159 |
| Chain | Residue |
| A | GLY120 |
| A | LYS121 |
| A | LYS141 |
| A | HOH2186 |
| B | ARG118 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A1160 |
| Chain | Residue |
| A | HIS41 |
| A | HIS43 |
| A | HOH2100 |
| A | HOH2187 |
| A | HOH2188 |
| A | HOH2190 |
| A | HOH2191 |
| B | ASN107 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A1161 |
| Chain | Residue |
| A | HIS70 |
| A | ASN73 |
| A | ARG74 |
| A | GLU122 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A1162 |
| Chain | Residue |
| A | LYS121 |
| A | THR140 |
| A | LYS141 |
| A | HOH2167 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A1163 |
| Chain | Residue |
| A | GLU44 |
| A | LEU45 |
| A | ASN46 |
| A | HOH2192 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A1164 |
| Chain | Residue |
| A | HIS70 |
| A | LYS71 |
| A | ARG74 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A1165 |
| Chain | Residue |
| A | CYS23 |
| A | CYS26 |
| A | CYS58 |
| A | CYS61 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B1158 |
| Chain | Residue |
| B | TYR8 |
| B | LYS12 |
| B | HIS38 |
| B | LEU39 |
| B | HOH2224 |
| B | HOH2225 |
| B | HOH2233 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1159 |
| Chain | Residue |
| B | VAL109 |
| B | LYS149 |
| B | ARG153 |
| B | HOH2155 |
| B | HOH2227 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 B1160 |
| Chain | Residue |
| B | HIS41 |
| B | ASP42 |
| B | HIS43 |
| B | ARG54 |
| B | GLU65 |
| B | LYS69 |
| B | HOH2070 |
| B | HOH2228 |
| B | HOH2229 |
| B | HOH2230 |
| B | HOH2231 |
| B | HOH2232 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1161 |
| Chain | Residue |
| A | ASN107 |
| B | HIS38 |
| B | HIS41 |
| B | HIS43 |
| B | HOH2233 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1162 |
| Chain | Residue |
| A | ARG118 |
| B | GLY120 |
| B | LYS121 |
| B | LYS141 |
| B | HOH2234 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B1163 |
| Chain | Residue |
| B | LYS121 |
| B | THR140 |
| B | LYS141 |
| B | HOH2235 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1164 |
| Chain | Residue |
| B | HIS70 |
| B | ASN73 |
| B | ARG74 |
| B | GLU122 |
| B | HOH2175 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B1165 |
| Chain | Residue |
| B | CYS23 |
| B | CYS26 |
| B | CYS58 |
| B | CYS61 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS23 | |
| B | CYS58 | |
| B | CYS61 | |
| B | ASP62 | |
| A | CYS26 | |
| A | ASP40 | |
| A | CYS58 | |
| A | CYS61 | |
| A | ASP62 | |
| B | CYS23 | |
| B | CYS26 | |
| B | ASP40 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 11327769 |
| Chain | Residue | Details |
| A | HIS43 | |
| A | GLU65 | |
| A | HIS41 | |
| B | HIS105 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | a catalytic site defined by CSA, PubMed 11327769 |
| Chain | Residue | Details |
| B | HIS43 | |
| B | GLU65 | |
| B | HIS41 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 11327769 |
| Chain | Residue | Details |
| A | HIS43 | |
| A | GLU65 | |
| A | HIS41 | |
| B | HIS105 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 11327769 |
| Chain | Residue | Details |
| A | HIS105 | |
| B | HIS41 | |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 161 |
| Chain | Residue | Details |
| A | ASP40 | metal ligand |
| A | HIS41 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS43 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP62 | metal ligand |
| A | GLU65 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS105 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 161 |
| Chain | Residue | Details |
| B | ASP40 | metal ligand |
| B | HIS41 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | HIS43 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP62 | metal ligand |
| B | GLU65 | electrostatic stabiliser, hydrogen bond donor |
| B | HIS105 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
