1E4W

crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0030183	biological_process	B cell differentiation
L	0042105	cellular_component	alpha-beta T cell receptor complex
L	0071735	cellular_component	IgG immunoglobulin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NI L 901

Chain	Residue
L	ASP1
L	HIS189
L	HOH2003
L	HOH2009

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL P 901

Chain	Residue
H	ARG56
H	ASN58
H	HOH2017
P	ASN4

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	92
Details	Domain: {"description":"Ig-like 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	97
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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