1E17

Solution structure of the DNA binding domain of the human Forkhead transcription factor AFX (FOXO4)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WKNSIRH

Chain	Residue	Details
A	TRP146-HIS152

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	DNA_BIND: Fork-head => ECO:0000255|PROSITE-ProRule:PRU00089

Chain	Residue	Details
A	GLN100-ARG188

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKB/AKT1 => ECO:0000269|PubMed:10217147, ECO:0000269|PubMed:10518537, ECO:0000269|PubMed:16272144

Chain	Residue	Details
A	SER197

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