1DZT
RMLC FROM SALMONELLA TYPHIMURIUM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0005829 | cellular_component | cytosol |
| A | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0009243 | biological_process | O antigen biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0009243 | biological_process | O antigen biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ARG60 |
| A | HIS63 |
| A | LYS73 |
| A | HIS120 |
| A | TYR133 |
| A | HOH2165 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | TYR133 |
| B | ATY1000 |
| B | HIS63 |
| B | LYS73 |
| B | HIS120 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE TPE A 1000 |
| Chain | Residue |
| A | LYS18 |
| A | GLN48 |
| A | ARG60 |
| A | TYR139 |
| A | SER167 |
| A | LYS169 |
| A | HOH2145 |
| A | HOH2146 |
| A | HOH3001 |
| A | HOH3002 |
| B | PHE20 |
| B | ARG24 |
| B | PHE27 |
| B | GLU29 |
| B | TYR139 |
| B | PRO141 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ATY B 1000 |
| Chain | Residue |
| A | PHE27 |
| A | GLU29 |
| A | PRO141 |
| A | SER142 |
| A | HOH3004 |
| B | GLN48 |
| B | ASN50 |
| B | HIS63 |
| B | TYR133 |
| B | TYR139 |
| B | GLU144 |
| B | SER167 |
| B | LYS169 |
| B | SO4302 |
| B | HOH2050 |
| B | HOH2117 |
| B | HOH3005 |
| B | HOH3006 |
| B | HOH3007 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 201 |
| Chain | Residue |
| B | TRP99 |
| B | GLY101 |
| B | HOH2147 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 202 |
| Chain | Residue |
| A | PHE20 |
| A | GLY25 |
| A | SER142 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 203 |
| Chain | Residue |
| A | TRP99 |
| A | VAL100 |
| A | GLY101 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 204 |
| Chain | Residue |
| A | GLU81 |
| A | LEU125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"10802738","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17046787","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DZR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1DZT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"10802738","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17046787","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DZT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9HU21","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10802738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DZT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10802738","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1DZT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10802738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DZR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1DZT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose","evidences":[{"source":"UniProtKB","id":"Q5SFD1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dzr |
| Chain | Residue | Details |
| A | ASP170 | |
| A | HIS63 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dzr |
| Chain | Residue | Details |
| B | ASP170 | |
| B | HIS63 |
