1DZR
RmlC from Salmonella typhimurium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0009243 | biological_process | O antigen biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0009243 | biological_process | O antigen biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ARG60 |
| A | HIS63 |
| A | LYS73 |
| A | HIS120 |
| A | TYR133 |
| A | TYR139 |
| A | HOH2153 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| Chain | Residue |
| B | HIS120 |
| B | TYR133 |
| B | TYR139 |
| B | HIS63 |
| B | LYS73 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ASN103 |
| A | ARG110 |
| A | HOH2154 |
| A | HOH2155 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | ASN103 |
| B | ARG110 |
| B | HOH2126 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 201 |
| Chain | Residue |
| A | MET2 |
| A | PRO17 |
| A | GLU29 |
| A | SER30 |
| A | TYR31 |
| A | ASN32 |
| A | PHE36 |
| A | GLN111 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 202 |
| Chain | Residue |
| A | MET1 |
| A | MET2 |
| A | LYS18 |
| A | HOH2145 |
| B | MET1 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 203 |
| Chain | Residue |
| A | GLY21 |
| A | GLY25 |
| A | HOH2146 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 204 |
| Chain | Residue |
| A | TRP99 |
| A | GLY101 |
| A | HOH2148 |
| A | HOH2149 |
| A | HOH2150 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 205 |
| Chain | Residue |
| A | ARG60 |
| A | HIS63 |
| A | SER167 |
| A | LYS169 |
| A | ASP170 |
| A | HOH2151 |
| A | HOH2152 |
| B | ARG24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:10802738, ECO:0000269|PubMed:17046787, ECO:0007744|PDB:1DZR, ECO:0007744|PDB:1DZT |
| Chain | Residue | Details |
| A | HIS63 | |
| B | HIS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000269|PubMed:10802738, ECO:0000269|PubMed:17046787, ECO:0007744|PDB:1DZT |
| Chain | Residue | Details |
| A | TYR133 | |
| B | TYR133 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9HU21 |
| Chain | Residue | Details |
| A | ARG24 | |
| A | GLU144 | |
| B | ARG24 | |
| B | GLU144 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10802738, ECO:0007744|PDB:1DZT |
| Chain | Residue | Details |
| A | GLU29 | |
| A | LYS169 | |
| B | GLU29 | |
| B | LYS169 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:10802738, ECO:0007744|PDB:1DZT |
| Chain | Residue | Details |
| A | GLN48 | |
| B | GLN48 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10802738, ECO:0007744|PDB:1DZR, ECO:0007744|PDB:1DZT |
| Chain | Residue | Details |
| A | ARG60 | |
| A | LYS73 | |
| A | HIS120 | |
| B | ARG60 | |
| B | LYS73 | |
| B | HIS120 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose => ECO:0000250|UniProtKB:Q5SFD1 |
| Chain | Residue | Details |
| A | TYR139 | |
| B | TYR139 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 10802738 |
| Chain | Residue | Details |
| A | ASP170 | |
| A | HIS63 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 10802738 |
| Chain | Residue | Details |
| B | ASP170 | |
| B | HIS63 |
