Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008720 | molecular_function | D-lactate dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
| A | 0097256 | molecular_function | phenyllactate dehydrogenase (NAD+) activity |
| A | 0140175 | molecular_function | (2R)-2-hydroxyacid dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 338 |
| Chain | Residue |
| A | GLY78 |
| A | TYR100 |
| A | ARG234 |
| A | COI404 |
| A | ASN76 |
| A | VAL77 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 339 |
| Chain | Residue |
| A | PRO98 |
| A | ALA99 |
| A | PHE310 |
| A | HIS314 |
| A | THR326 |
| A | HOH653 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAD A 336 |
| Chain | Residue |
| A | TYR100 |
| A | GLY152 |
| A | GLY154 |
| A | HIS155 |
| A | ILE156 |
| A | TYR174 |
| A | ASP175 |
| A | PRO176 |
| A | HIS204 |
| A | VAL205 |
| A | PRO206 |
| A | ASN211 |
| A | ILE214 |
| A | THR232 |
| A | ALA233 |
| A | ARG234 |
| A | ASP258 |
| A | THR259 |
| A | HIS295 |
| A | TYR298 |
| A | COI404 |
| A | HOH502 |
| A | HOH504 |
| A | HOH580 |
| A | HOH581 |
| A | HOH629 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE COI A 337 |
| Chain | Residue |
| A | VAL77 |
| A | TYR100 |
| A | ARG234 |
| A | HIS295 |
| A | MET307 |
| A | NAD403 |
| A | SO4401 |
| site_id | CAT |
| Number of Residues | 7 |
| Details | ACTIVE SITE. |
| Chain | Residue |
| A | VAL77 |
| A | GLY78 |
| A | TYR100 |
| A | THR232 |
| A | ARG234 |
| A | GLU263 |
| A | HIS295 |
Functional Information from PROSITE/UniProt
| site_id | PS00065 |
| Number of Residues | 28 |
| Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGVMGtGHIGqvaiklfkgfgak.VIaYD |
| Chain | Residue | Details |
| A | VAL148-ASP175 | |
| site_id | PS00670 |
| Number of Residues | 23 |
| Details | D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. LFkqSDVIdLHvPgieqNthIiN |
| Chain | Residue | Details |
| A | LEU194-ASN216 | |
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKpGaIVINtARPnLID |
| Chain | Residue | Details |
| A | MET223-ASP239 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"9126843","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"9126843","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9126843","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DXY","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1j49 |
| Chain | Residue | Details |
| A | GLY207 | |
| A | ARG234 | |
| A | ASP258 | |
| A | GLU263 | |
| A | HIS295 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1j49 |
| Chain | Residue | Details |
| A | GLU263 | |
| A | HIS295 | |
