Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1DX0

BOVINE PRION PROTEIN RESIDUES 23-230

Functional Information from GO Data
ChainGOidnamespacecontents
A0001540molecular_functionamyloid-beta binding
A0002151molecular_functionG-quadruplex RNA binding
A0005507molecular_functioncopper ion binding
A0005515molecular_functionprotein binding
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0008017molecular_functionmicrotubule binding
A0009986cellular_componentcell surface
A0015631molecular_functiontubulin binding
A0016020cellular_componentmembrane
A0016234cellular_componentinclusion body
A0030425cellular_componentdendrite
A0031648biological_processprotein destabilization
A0031802molecular_functiontype 5 metabotropic glutamate receptor binding
A0031965cellular_componentnuclear membrane
A0035584biological_processobsolete calcium-mediated signaling using intracellular calcium source
A0042802molecular_functionidentical protein binding
A0043231cellular_componentintracellular membrane-bounded organelle
A0043525biological_processpositive regulation of neuron apoptotic process
A0044877molecular_functionprotein-containing complex binding
A0045121cellular_componentmembrane raft
A0046872molecular_functionmetal ion binding
A0050731biological_processpositive regulation of peptidyl-tyrosine phosphorylation
A0051260biological_processprotein homooligomerization
A0060090molecular_functionmolecular adaptor activity
A0071280biological_processcellular response to copper ion
A0098552cellular_componentside of membrane
A0140693molecular_functionmolecular condensate scaffold activity
A1903136molecular_functioncuprous ion binding
A1904646biological_processcellular response to amyloid-beta
Functional Information from PROSITE/UniProt
site_idPS00291
Number of Residues16
DetailsPRION_1 Prion protein signature 1. AGAAAAGAVVGGLGGY
ChainResidueDetails
AALA113-TYR128

site_idPS00706
Number of Residues19
DetailsPRION_2 Prion protein signature 2. EtDiKMMeRVVeQMCitQY
ChainResidueDetails
AGLU200-TYR218

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P04156
ChainResidueDetails
AHIS672
AHIS85
AGLY87
AGLY871
AGLY673
AGLY674
AHIS69
AGLY70
AGLY71
AHIS77
AGLY78
AGLY79

site_idSWS_FT_FI2
Number of Residues1
DetailsLIPID: GPI-anchor amidated alanine => ECO:0000255
ChainResidueDetails
AALA230

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305
ChainResidueDetails
AASN181
AASN197

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon