1DVP

CRYSTAL STRUCTURE OF THE VHS AND FYVE TANDEM DOMAINS OF HRS, A PROTEIN INVOLVED IN MEMBRANE TRAFFICKING AND SIGNAL TRANSDUCTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0035091	molecular_function	phosphatidylinositol binding
A	0043130	molecular_function	ubiquitin binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS164
A	CYS167
A	CYS188
A	CYS191

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 402

Chain	Residue
A	CYS180
A	CYS183
A	CYS210
A	CYS213

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site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CIT A 300

Chain	Residue
A	ARG176
A	HIS178
A	HIS179
A	ARG181
A	ARG181
A	ARG208
A	HOH463
A	HOH498
A	HOH520
A	HOH598
A	TRP158

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	128
Details	Domain: {"description":"VHS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00218","evidenceCode":"ECO:0000255"},{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	60
Details	Zinc finger: {"description":"FYVE-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00091","evidenceCode":"ECO:0000255"},{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00091","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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