1DVI

CALPAIN DOMAIN VI WITH CALCIUM BOUND

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
B	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 271

Chain	Residue
A	ALA111
A	ASP114
A	GLU116
A	GLU121
A	HOH284
A	HOH296

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 272

Chain	Residue
A	LYS160
A	GLU165
A	HOH275
A	ASP154
A	ASP156
A	THR158

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 273

Chain	Residue
A	ASP184
A	ASP186
A	SER188
A	THR190
A	GLU195
A	HOH278

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 274

Chain	Residue
A	ASP139
A	ASP227
A	ASP229
A	ASN230
B	HOH282
B	HOH285

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 275

Chain	Residue
B	ALA111
B	ASP114
B	GLU116
B	GLU121
B	HOH302
B	HOH314

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 276

Chain	Residue
B	ASP154
B	ASP156
B	THR158
B	LYS160
B	GLU165
B	HOH292

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 277

Chain	Residue
B	ASP184
B	ASP186
B	SER188
B	THR190
B	GLU195
B	HOH295

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 278

Chain	Residue
B	ASP139
B	ASP227
B	ASP229
B	ASN230
B	HOH301
B	HOH315

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DSDTTGKLGfeEF

Chain	Residue	Details
A	ASP154-PHE166
A	ASP184-LEU196

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	Domain: {"description":"EF-hand 1; atypical","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	66
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	70
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	56
Details	Domain: {"description":"EF-hand 4","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	68
Details	Domain: {"description":"EF-hand 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19020622","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19020623","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9228945","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DVI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BOW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3DF0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19020622","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19020623","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9228945","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DVI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BOW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3DF0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P04632","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---