Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1DPS

THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006950	biological_process	response to stress
A	0008199	molecular_function	ferric iron binding
A	0009295	cellular_component	nucleoid
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016722	molecular_function	oxidoreductase activity, acting on metal ions
A	0030261	biological_process	chromosome condensation
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042594	biological_process	response to starvation
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	1990084	cellular_component	DnaA-Dps complex
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006950	biological_process	response to stress
B	0008199	molecular_function	ferric iron binding
B	0009295	cellular_component	nucleoid
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016722	molecular_function	oxidoreductase activity, acting on metal ions
B	0030261	biological_process	chromosome condensation
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042594	biological_process	response to starvation
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	1990084	cellular_component	DnaA-Dps complex
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006950	biological_process	response to stress
C	0008199	molecular_function	ferric iron binding
C	0009295	cellular_component	nucleoid
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016722	molecular_function	oxidoreductase activity, acting on metal ions
C	0030261	biological_process	chromosome condensation
C	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
C	0042594	biological_process	response to starvation
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	1990084	cellular_component	DnaA-Dps complex
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006950	biological_process	response to stress
D	0008199	molecular_function	ferric iron binding
D	0009295	cellular_component	nucleoid
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016722	molecular_function	oxidoreductase activity, acting on metal ions
D	0030261	biological_process	chromosome condensation
D	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
D	0042594	biological_process	response to starvation
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	1990084	cellular_component	DnaA-Dps complex
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006950	biological_process	response to stress
E	0008199	molecular_function	ferric iron binding
E	0009295	cellular_component	nucleoid
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0016722	molecular_function	oxidoreductase activity, acting on metal ions
E	0030261	biological_process	chromosome condensation
E	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
E	0042594	biological_process	response to starvation
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	1990084	cellular_component	DnaA-Dps complex
F	0003677	molecular_function	DNA binding
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006950	biological_process	response to stress
F	0008199	molecular_function	ferric iron binding
F	0009295	cellular_component	nucleoid
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0016722	molecular_function	oxidoreductase activity, acting on metal ions
F	0030261	biological_process	chromosome condensation
F	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
F	0042594	biological_process	response to starvation
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	1990084	cellular_component	DnaA-Dps complex
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006950	biological_process	response to stress
G	0008199	molecular_function	ferric iron binding
G	0009295	cellular_component	nucleoid
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016722	molecular_function	oxidoreductase activity, acting on metal ions
G	0030261	biological_process	chromosome condensation
G	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
G	0042594	biological_process	response to starvation
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	1990084	cellular_component	DnaA-Dps complex
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006950	biological_process	response to stress
H	0008199	molecular_function	ferric iron binding
H	0009295	cellular_component	nucleoid
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0016722	molecular_function	oxidoreductase activity, acting on metal ions
H	0030261	biological_process	chromosome condensation
H	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
H	0042594	biological_process	response to starvation
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	1990084	cellular_component	DnaA-Dps complex
I	0003677	molecular_function	DNA binding
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006950	biological_process	response to stress
I	0008199	molecular_function	ferric iron binding
I	0009295	cellular_component	nucleoid
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0016722	molecular_function	oxidoreductase activity, acting on metal ions
I	0030261	biological_process	chromosome condensation
I	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
I	0042594	biological_process	response to starvation
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
I	1990084	cellular_component	DnaA-Dps complex
J	0003677	molecular_function	DNA binding
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006950	biological_process	response to stress
J	0008199	molecular_function	ferric iron binding
J	0009295	cellular_component	nucleoid
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0016722	molecular_function	oxidoreductase activity, acting on metal ions
J	0030261	biological_process	chromosome condensation
J	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
J	0042594	biological_process	response to starvation
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
J	1990084	cellular_component	DnaA-Dps complex
K	0003677	molecular_function	DNA binding
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006950	biological_process	response to stress
K	0008199	molecular_function	ferric iron binding
K	0009295	cellular_component	nucleoid
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0016722	molecular_function	oxidoreductase activity, acting on metal ions
K	0030261	biological_process	chromosome condensation
K	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
K	0042594	biological_process	response to starvation
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
K	1990084	cellular_component	DnaA-Dps complex
L	0003677	molecular_function	DNA binding
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006950	biological_process	response to stress
L	0008199	molecular_function	ferric iron binding
L	0009295	cellular_component	nucleoid
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0016722	molecular_function	oxidoreductase activity, acting on metal ions
L	0030261	biological_process	chromosome condensation
L	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
L	0042594	biological_process	response to starvation
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
L	1990084	cellular_component	DnaA-Dps complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 168

Chain	Residue
A	LYS140
A	ASP142
A	HOH211
A	HOH219
A	HOH235

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 168

Chain	Residue
B	HOH245
B	LYS140
B	ASP142
B	HOH213
B	HOH221

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA C 168

Chain	Residue
C	LYS140
C	ASP142
C	HOH221
C	HOH228
C	HOH239

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA D 168

Chain	Residue
D	LYS140
D	ASP142
D	HOH220
D	HOH227
D	HOH263

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA E 168

Chain	Residue
E	LYS140
E	ASP142
E	HOH216
E	HOH236
E	HOH267

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA F 168

Chain	Residue
F	LYS140
F	ASP142
F	HOH219
F	HOH227
F	HOH250
F	HOH276

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA G 168

Chain	Residue
G	LYS140
G	ASP142
G	HOH225
G	HOH232
G	HOH242

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA H 168

Chain	Residue
H	LYS140
H	ASP142
H	HOH226
H	HOH234
H	HOH240
H	HOH266

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA I 168

Chain	Residue
I	LYS140
I	ASP142
I	HOH169
I	HOH235
I	HOH241

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA J 168

Chain	Residue
J	LYS140
J	ASP142
J	HOH173
J	HOH228
J	HOH236
J	HOH274

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA K 168

Chain	Residue
K	LYS140
K	ASP142
K	HOH175
K	HOH238
K	HOH246

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA L 168

Chain	Residue
L	LYS140
L	ASP142
L	HOH169
L	HOH239
L	HOH247

Functional Information from PROSITE/UniProt

site_id	PS00818
Number of Residues	17
Details	DPS_1 Dps protein family signature 1. HWnMrGanfiaVHemlD

Chain	Residue	Details
A	HIS51-ASP67

site_id	PS00819
Number of Residues	15
Details	DPS_2 Dps protein family signature 2. LDtMAERavqLGgvA

Chain	Residue	Details
A	LEU77-ALA91

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	TRP52
J	TRP52
K	TRP52
L	TRP52
B	TRP52
C	TRP52
D	TRP52
E	TRP52
F	TRP52
G	TRP52
H	TRP52
I	TRP52

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: in other chain

Chain	Residue	Details
A	THR79
J	THR79
K	THR79
L	THR79
B	THR79
C	THR79
D	THR79
E	THR79
F	THR79
G	THR79
H	THR79
I	THR79

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	ARG83
J	ARG83
K	ARG83
L	ARG83
B	ARG83
C	ARG83
D	ARG83
E	ARG83
F	ARG83
G	ARG83
H	ARG83
I	ARG83

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)