Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007584 | biological_process | response to nutrient |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030574 | biological_process | collagen catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 246 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH347 |
| A | HOH353 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 250 |
| Chain | Residue |
| A | ASN100 |
| A | ASN101 |
| A | ASN179 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 251 |
| Chain | Residue |
| A | ALA132 |
| A | PRO164 |
| A | GLN165 |
| A | HOH358 |
| A | HOH359 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BEN A 247 |
| Chain | Residue |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | GLY226 |
| A | HOH325 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BEN A 248 |
| Chain | Residue |
| A | SER146 |
| A | GLY188 |
| A | ALA221 |
| A | ALA221 |
| A | LEU221 |
| A | PRO222 |
| A | HOH400 |
| A | HOH401 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BEN A 249 |
| Chain | Residue |
| A | ARG62 |
| A | ILE63 |
| A | GLN64 |
| site_id | CAT |
| Number of Residues | 3 |
| Details | CATALYTIC TRIAD. |
| Chain | Residue |
| A | HIS57 |
| A | ASP102 |
| A | CYS195 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for specificity","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | CYS195 | |
| A | GLY196 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | CYS195 | |
| A | GLY193 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | CYS195 | |
| A | HIS57 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | CYS195 | |
| A | GLY193 | |
| A | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | HIS57 | |
