1DLV
BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA IN COMPLEX WITH COA
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003985 | molecular_function | acetyl-CoA C-acetyltransferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0016746 | molecular_function | acyltransferase activity |
A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
A | 0042619 | biological_process | poly-hydroxybutyrate biosynthetic process |
B | 0003985 | molecular_function | acetyl-CoA C-acetyltransferase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0016746 | molecular_function | acyltransferase activity |
B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
B | 0042619 | biological_process | poly-hydroxybutyrate biosynthetic process |
C | 0003985 | molecular_function | acetyl-CoA C-acetyltransferase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0016746 | molecular_function | acyltransferase activity |
C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
C | 0042619 | biological_process | poly-hydroxybutyrate biosynthetic process |
D | 0003985 | molecular_function | acetyl-CoA C-acetyltransferase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0016746 | molecular_function | acyltransferase activity |
D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
D | 0042619 | biological_process | poly-hydroxybutyrate biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 5001 |
Chain | Residue |
B | LYS298 |
B | ARG302 |
B | HOH5175 |
B | HOH5221 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 5002 |
Chain | Residue |
A | SER260 |
A | ALA262 |
A | GLU263 |
A | ARG266 |
A | HOH5180 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 5003 |
Chain | Residue |
B | SER260 |
B | GLU263 |
B | ARG266 |
B | HOH5184 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 5004 |
Chain | Residue |
A | ARG302 |
A | HOH5156 |
A | HOH5282 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 5005 |
Chain | Residue |
A | ARG41 |
A | ILE199 |
A | VAL200 |
A | PRO201 |
A | HOH5159 |
A | HOH5256 |
A | HOH5291 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 B 5006 |
Chain | Residue |
B | ARG41 |
B | ILE199 |
B | VAL200 |
B | PRO201 |
B | HOH5176 |
B | HOH5242 |
B | HOH5245 |
site_id | AC7 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE COA A 1001 |
Chain | Residue |
A | LEU148 |
A | HIS156 |
A | MET157 |
A | ARG220 |
A | SER227 |
A | LEU231 |
A | ALA243 |
A | GLY244 |
A | SER247 |
A | MET288 |
A | PHE319 |
A | HOH5092 |
A | HOH5098 |
A | HOH5126 |
A | HOH5167 |
A | HOH5170 |
D | MET134 |
site_id | AC8 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE COA B 2001 |
Chain | Residue |
B | LEU148 |
B | HIS156 |
B | MET157 |
B | ARG220 |
B | SER227 |
B | MET228 |
B | PHE235 |
B | ALA243 |
B | GLY244 |
B | SER247 |
B | MET288 |
B | PHE319 |
B | HOH5023 |
B | HOH5051 |
B | HOH5056 |
B | HOH5090 |
B | HOH5214 |
site_id | AC9 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE COA C 3001 |
Chain | Residue |
C | LEU148 |
C | HIS156 |
C | MET157 |
C | ARG220 |
C | SER227 |
C | MET228 |
C | PHE235 |
C | ALA243 |
C | GLY244 |
C | SER247 |
C | MET288 |
C | PHE319 |
C | HIS348 |
site_id | BC1 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE COA D 4001 |
Chain | Residue |
D | LEU148 |
D | HIS156 |
D | MET157 |
D | ARG220 |
D | SER227 |
D | MET228 |
D | LEU231 |
D | ALA243 |
D | GLY244 |
D | SER247 |
D | MET288 |
D | PHE319 |
D | HIS348 |
D | HOH4039 |
Functional Information from PROSITE/UniProt
site_id | PS00098 |
Number of Residues | 19 |
Details | THIOLASE_1 Thiolases acyl-enzyme intermediate signature. MNQlCGSGLrAValgmqqI |
Chain | Residue | Details |
A | MET85-ILE103 |
site_id | PS00099 |
Number of Residues | 14 |
Details | THIOLASE_3 Thiolases active site. GLATLCIGgGmGvA |
Chain | Residue | Details |
A | GLY373-ALA386 |
site_id | PS00737 |
Number of Residues | 17 |
Details | THIOLASE_2 Thiolases signature 2. NvnGGaIAiGHPiGaSG |
Chain | Residue | Details |
A | ASN338-GLY354 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Acyl-thioester intermediate |
Chain | Residue | Details |
A | CYS89 | |
B | CYS89 | |
C | CYS89 | |
D | CYS89 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | HIS348 | |
A | CYS378 | |
B | HIS348 | |
B | CYS378 | |
C | HIS348 | |
C | CYS378 | |
D | HIS348 | |
D | CYS378 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
A | HIS348 | |
A | GLY380 | |
A | CYS378 | |
A | CYS89 |
site_id | CSA2 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
B | HIS348 | |
B | GLY380 | |
B | CYS378 | |
B | CYS89 |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
C | HIS348 | |
C | GLY380 | |
C | CYS378 | |
C | CYS89 |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
D | HIS348 | |
D | GLY380 | |
D | CYS378 | |
D | CYS89 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
A | HIS348 | |
A | CYS378 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
B | HIS348 | |
B | CYS378 |
site_id | CSA7 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
C | HIS348 | |
C | CYS378 |
site_id | CSA8 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1afw |
Chain | Residue | Details |
D | HIS348 | |
D | CYS378 |