1DIX

CRYSTAL STRUCTURE OF RNASE LE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005576	cellular_component	extracellular region
A	0006401	biological_process	RNA catabolic process
A	0016829	molecular_function	lyase activity
A	0033897	molecular_function	ribonuclease T2 activity

Functional Information from PROSITE/UniProt

site_id	PS00530
Number of Residues	8
Details	RNASE_T2_1 Ribonuclease T2 family histidine active site 1. FgIHGLWP

Chain	Residue	Details
A	PHE36-PRO43

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site_id	PS00531
Number of Residues	12
Details	RNASE_T2_2 Ribonuclease T2 family histidine active site 2. FwsHEWeKHGtC

Chain	Residue	Details
A	PHE89-CYS100

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q7SID5, ECO:0000255|PROSITE-ProRule:PRU10045

Chain	Residue	Details
A	HIS39

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P08056

Chain	Residue	Details
A	GLU93

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site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q7SID5, ECO:0000255|PROSITE-ProRule:PRU10045

Chain	Residue	Details
A	HIS97

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site_id	SWS_FT_FI4
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P23540

Chain	Residue	Details
A	GLN12
A	HIS39
A	PHE89
A	HIS92
A	LYS96

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1bol

Chain	Residue	Details
A	HIS97
A	HIS39
A	GLU93

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