1DIX

CRYSTAL STRUCTURE OF RNASE LE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005576	cellular_component	extracellular region
A	0006401	biological_process	RNA catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016829	molecular_function	lyase activity
A	0033897	molecular_function	ribonuclease T2 activity

Functional Information from PROSITE/UniProt

site_id	PS00530
Number of Residues	8
Details	RNASE_T2_1 Ribonuclease T2 family histidine active site 1. FgIHGLWP

Chain	Residue	Details
A	PHE36-PRO43

---

site_id	PS00531
Number of Residues	12
Details	RNASE_T2_2 Ribonuclease T2 family histidine active site 2. FwsHEWeKHGtC

Chain	Residue	Details
A	PHE89-CYS100

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"Q7SID5","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10045","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P08056","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q7SID5","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10045","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P23540","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1bol

Chain	Residue	Details
A	HIS97
A	HIS39
A	GLU93

---