Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001889 | biological_process | liver development |
| A | 0004155 | molecular_function | 6,7-dihydropteridine reductase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
| A | 0010044 | biological_process | response to aluminum ion |
| A | 0010288 | biological_process | response to lead ion |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0033762 | biological_process | response to glucagon |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0070402 | molecular_function | NADPH binding |
| A | 0070404 | molecular_function | NADH binding |
| A | 0071466 | biological_process | cellular response to xenobiotic stimulus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAD A 241 |
| Chain | Residue |
| A | TYR12 |
| A | LYS69 |
| A | VAL82 |
| A | ALA83 |
| A | GLY84 |
| A | GLY85 |
| A | LYS105 |
| A | GLN106 |
| A | THR110 |
| A | ALA131 |
| A | TYR146 |
| A | ARG15 |
| A | LYS150 |
| A | VAL179 |
| A | THR180 |
| A | LEU181 |
| A | ASN186 |
| A | HOH245 |
| A | HOH248 |
| A | HOH254 |
| A | HOH275 |
| A | HOH279 |
| A | GLY16 |
| A | HOH300 |
| A | HOH308 |
| A | ALA17 |
| A | LEU18 |
| A | ASP37 |
| A | VAL38 |
| A | VAL50 |
| A | GLN59 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. AkaaldgtpgMigYGMAKGAVhQLCqSLA |
| Chain | Residue | Details |
| A | ALA133-ALA161 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q8BVI4","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 8202530, 11976334 |
| Chain | Residue | Details |
| A | LYS150 | |
| A | TYR146 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 491 |
| Chain | Residue | Details |
| A | TYR146 | electrostatic stabiliser, proton shuttle (general acid/base) |
| A | LYS150 | electrostatic stabiliser, proton shuttle (general acid/base) |
