Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003911 | molecular_function | DNA ligase (NAD+) activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003911 | molecular_function | DNA ligase (NAD+) activity |
| B | 0006260 | biological_process | DNA replication |
| B | 0006281 | biological_process | DNA repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 701 |
| Chain | Residue |
| A | CYS406 |
| A | CYS409 |
| A | CYS422 |
| A | CYS427 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2701 |
| Chain | Residue |
| B | CYS2406 |
| B | CYS2409 |
| B | CYS2422 |
| B | CYS2427 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AMP A 700 |
| Chain | Residue |
| A | GLU114 |
| A | HIS115 |
| A | LYS116 |
| A | VAL117 |
| A | GLU169 |
| A | ARG196 |
| A | TYR221 |
| A | HIS253 |
| A | LYS312 |
| A | LEU85 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AMP B 2700 |
| Chain | Residue |
| B | HOH1100 |
| B | LEU2085 |
| B | GLU2114 |
| B | HIS2115 |
| B | LYS2116 |
| B | VAL2117 |
| B | LEU2120 |
| B | GLU2169 |
| B | ARG2196 |
| B | TYR2221 |
| B | LYS2312 |
Functional Information from PROSITE/UniProt
| site_id | PS01056 |
| Number of Residues | 16 |
| Details | DNA_LIGASE_N2 NAD-dependent DNA ligase signature 2. VGRTGrVTpVgvLePV |
| Chain | Residue | Details |
| A | VAL329-VAL344 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP118 | |
| B | ASP2118 | |
| Chain | Residue | Details |
| A | ASP34 | |
| B | ILE2174 | |
| B | GLY2226 | |
| B | LYS2288 | |
| A | SER84 | |
| A | VAL139 | |
| A | ILE174 | |
| A | GLY226 | |
| A | LYS288 | |
| B | ASP2034 | |
| B | SER2084 | |
| B | VAL2139 | |
| Chain | Residue | Details |
| A | LYS116 | |
| B | LYS2116 | |
| Chain | Residue | Details |
| A | LYS312 | |
| B | LYS2312 | |
| Chain | Residue | Details |
| A | CYS406 | |
| A | CYS409 | |
| A | CYS422 | |
| A | CYS427 | |
| B | CYS2406 | |
| B | CYS2409 | |
| B | CYS2422 | |
| B | CYS2427 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 9 |
| Details | M-CSA 450 |
| Chain | Residue | Details |
| A | LYS116 | electrostatic stabiliser |
| A | ASP118 | covalent catalysis |
| A | LEU120 | electrostatic stabiliser |
| A | GLY226 | electrostatic stabiliser |
| A | LYS312 | electrostatic stabiliser |
| A | CYS406 | metal ligand |
| A | CYS409 | metal ligand |
| A | CYS422 | metal ligand |
| A | CYS427 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 9 |
| Details | M-CSA 450 |
| Chain | Residue | Details |
| B | LYS2116 | electrostatic stabiliser |
| B | ASP2118 | covalent catalysis |
| B | LEU2120 | electrostatic stabiliser |
| B | GLY2226 | electrostatic stabiliser |
| B | LYS2312 | electrostatic stabiliser |
| B | CYS2406 | metal ligand |
| B | CYS2409 | metal ligand |
| B | CYS2422 | metal ligand |
| B | CYS2427 | metal ligand |
