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1DGN

SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0004869molecular_functioncysteine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0006508biological_processproteolysis
A0006954biological_processinflammatory response
A0019899molecular_functionenzyme binding
A0030414molecular_functionpeptidase inhibitor activity
A0032091biological_processnegative regulation of protein binding
A0032651biological_processregulation of interleukin-1 beta production
A0032691biological_processnegative regulation of interleukin-1 beta production
A0032991cellular_componentprotein-containing complex
A0042981biological_processregulation of apoptotic process
A0050700molecular_functionCARD domain binding
A0089720molecular_functioncaspase binding

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PDB entries from 2025-06-18

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