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1D9S

TUMOR SUPPRESSOR P15(INK4B) STRUCTURE BY COMPARATIVE MODELING AND NMR DATA

Functional Information from GO Data
ChainGOidnamespacecontents
A0001889biological_processliver development
A0004861molecular_functioncyclin-dependent protein serine/threonine kinase inhibitor activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0007049biological_processcell cycle
A0008285biological_processnegative regulation of cell population proliferation
A0014070biological_processresponse to organic cyclic compound
A0019901molecular_functionprotein kinase binding
A0030219biological_processmegakaryocyte differentiation
A0030511biological_processpositive regulation of transforming growth factor beta receptor signaling pathway
A0030858biological_processpositive regulation of epithelial cell differentiation
A0031668biological_processobsolete cellular response to extracellular stimulus
A0031670biological_processcellular response to nutrient
A0034097biological_processresponse to cytokine
A0042326biological_processnegative regulation of phosphorylation
A0048536biological_processspleen development
A0050680biological_processnegative regulation of epithelial cell proliferation
A0060253biological_processnegative regulation of glial cell proliferation
A0070316biological_processregulation of G0 to G1 transition
A0071560biological_processcellular response to transforming growth factor beta stimulus
A0090398biological_processcellular senescence
A1902807biological_processnegative regulation of cell cycle G1/S phase transition
A2000045biological_processregulation of G1/S transition of mitotic cell cycle
A2000134biological_processnegative regulation of G1/S transition of mitotic cell cycle
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:15345747
ChainResidueDetails
ATHR12

218853

PDB entries from 2024-04-24

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