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1D9D

CRYSTALL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH SHORT DNA FRAGMENT CARRYING 2'-0-AMINOPROPYL-RNA MODIFICATIONS 5'-D(TCG)-AP(AUC)-3'

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0006139biological_processnucleobase-containing compound metabolic process
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0008408molecular_function3'-5' exonuclease activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN A 1
ChainResidue
AASP355
AGLU357
AASP501
BU311005
BC311006

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN A 3
ChainResidue
AGLU572
AHIS901
AGLU905

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN A 320
ChainResidue
AASP882
AHOH1068
AARG668

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 321
ChainResidue
ALEU723
ATHR737
AASN761
ATYR791

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN A 322
ChainResidue
AGLU883
AHIS928
AHOH1173

site_idAC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 32
ChainResidue
ALYS518
AHIS519
ALYS520

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 38
ChainResidue
ALYS520
AARG682
AHIS734
AARG754
ALYS758

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 40
ChainResidue
AGLU412
AARG436
AGLY437
AILE438
AHOH1011
AHOH1112

site_idAC9
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 94
ChainResidue
AARG400
AHOH1062

Functional Information from PROSITE/UniProt
site_idPS00447
Number of Residues20
DetailsDNA_POLYMERASE_A DNA polymerase family A signature. RrsAKainFGliYgmSafgL
ChainResidueDetails
AARG754-LEU773

227111

PDB entries from 2024-11-06

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