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1D5T

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM

Functional Information from GO Data
ChainGOidnamespacecontents
A0005092molecular_functionGDP-dissociation inhibitor activity
A0005093molecular_functionRab GDP-dissociation inhibitor activity
A0005096molecular_functionGTPase activator activity
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0007264biological_processsmall GTPase-mediated signal transduction
A0015031biological_processprotein transport
A0016192biological_processvesicle-mediated transport
A0030496cellular_componentmidbody
A0032482biological_processRab protein signal transduction
A0034123biological_processpositive regulation of toll-like receptor signaling pathway
A0050771biological_processnegative regulation of axonogenesis
A0090315biological_processnegative regulation of protein targeting to membrane
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 501
ChainResidue
ATYR117
ALYS118
AASN130
AHOH1032
AHOH1169
AHOH1324

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 502
ChainResidue
AHOH1064
AHOH1066
AHOH1316
ATYR192
AARG193
ATHR194

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P50396
ChainResidueDetails
ASER427

227344

PDB entries from 2024-11-13

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