1D4D

CRYSTAL STRUCTURE OF THE SUCCINATE COMPLEXED FORM OF THE FLAVOCYTOCHROME C FUMARATE REDUCTASE OF SHEWANELLA PUTREFACIENS STRAIN MR-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC A 601

Chain	Residue
A	SER62
A	HIS337
A	VAL373
A	GLY433
A	TYR434
A	LEU437
A	HIS63
A	LEU64
A	TYR83
A	CYS84
A	CYS87
A	HIS88
A	PHE90
A	LEU166

---

site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEC A 602

Chain	Residue
A	HIS42
A	GLY43
A	LEU45
A	LEU48
A	PRO59
A	HIS60
A	ILE68
A	ALA69
A	CYS70
A	CYS73
A	HIS74
A	ASP93
A	MET94
A	PRO95
A	ILE202
A	TYR360
A	HEC604
A	HOH720
A	HOH721
A	HOH722
A	HOH748

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC A 603

Chain	Residue
A	ALA6
A	GLY14
A	CYS15
A	CYS18
A	HIS19
A	LYS23
A	GLY24
A	GLY25
A	VAL26
A	THR71
A	LYS75
A	GLY76
A	HIS77
A	TYR297
A	HOH745

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC A 604

Chain	Residue
A	LEU5
A	PHE8
A	HIS9
A	SER17
A	GLN37
A	CYS38
A	CYS41
A	HIS42
A	HIS74
A	PRO95
A	ARG200
A	TYR325
A	ASP326
A	TYR360
A	HEC602

---

site_id	AC5
Number of Residues	43
Details	BINDING SITE FOR RESIDUE FAD A 600

Chain	Residue
A	ILE550
A	ILE553
A	SIN700
A	HOH701
A	HOH702
A	HOH704
A	HOH705
A	HOH717
A	HOH726
A	GLY132
A	SER133
A	GLY134
A	ALA136
A	LEU154
A	GLU155
A	LYS156
A	GLU157
A	GLY161
A	GLY162
A	ASN163
A	THR164
A	ALA167
A	ALA168
A	GLY169
A	GLY170
A	SER275
A	ARG276
A	VAL277
A	ALA312
A	GLY313
A	THR335
A	ASN336
A	HIS337
A	ASP343
A	MET374
A	HIS503
A	HIS504
A	GLY533
A	GLU534
A	ARG544
A	GLY547
A	ASN548
A	ALA549

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SIN A 700

Chain	Residue
A	GLY169
A	MET235
A	HIS364
A	THR376
A	GLU377
A	ARG401
A	HIS503
A	ARG544
A	GLY547
A	FAD600

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0C278","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"10581551","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1D4C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"10581551","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1D4C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10581551","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1D4C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10581551","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1D4D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1d4c

Chain	Residue	Details
A	ARG401
A	HIS503
A	HIS364
A	ARG544

---