Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1D4C

CRYSTAL STRUCTURE OF THE UNCOMPLEXED FORM OF THE FLAVOCYTOCHROME C FUMARATE REDUCTASE OF SHEWANELLA PUTREFACIENS STRAIN MR-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
B	0010181	molecular_function	FMN binding
B	0016491	molecular_function	oxidoreductase activity
C	0010181	molecular_function	FMN binding
C	0016491	molecular_function	oxidoreductase activity
D	0010181	molecular_function	FMN binding
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 814

Chain	Residue
C	ARG401
C	HIS503
C	ARG544
C	GLY546
C	GLY547
C	FAD800

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 714

Chain	Residue
B	HIS503
B	ARG544
B	GLY546
B	GLY547
B	FAD700
B	MET235
B	MET374
B	ARG401

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 914

Chain	Residue
D	ARG401
D	HIS503
D	ARG544
D	GLY546
D	GLY547
D	FAD900

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEC A 601

Chain	Residue
A	VAL57
A	SER62
A	HIS63
A	LEU64
A	TYR83
A	CYS84
A	CYS87
A	HIS88
A	PHE90
A	LEU166
A	HIS337
A	VAL373
A	GLY433
A	TYR434
A	LEU437
A	HOH612

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC A 602

Chain	Residue
A	HIS42
A	LEU45
A	LEU48
A	PRO59
A	HIS60
A	ILE68
A	ALA69
A	CYS70
A	CYS73
A	HIS74
A	ASP93
A	MET94
C	ILE202
C	TYR360

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEC A 603

Chain	Residue
A	ALA6
A	GLY14
A	CYS15
A	CYS18
A	HIS19
A	LYS23
A	THR71
A	LYS75
A	GLY76
A	HIS77
A	TYR297
A	HOH649

site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC A 604

Chain	Residue
A	PHE8
A	HIS9
A	MET12
A	SER17
A	GLN37
A	CYS38
A	CYS41
A	HIS42
A	HIS74
A	PRO95
C	ARG200
C	LYS324
C	TYR325
C	GLU359
C	TYR360

site_id	AC8
Number of Residues	36
Details	BINDING SITE FOR RESIDUE FAD A 600

Chain	Residue
A	HIS503
A	HIS504
A	GLY533
A	GLU534
A	ARG544
A	GLY547
A	ASN548
A	ALA549
A	ILE550
A	ILE553
A	HOH605
A	HOH607
A	HOH608
A	HOH638
A	GLY132
A	GLY134
A	ALA136
A	LEU154
A	GLU155
A	LYS156
A	GLU157
A	GLY162
A	ASN163
A	THR164
A	LEU166
A	ALA167
A	ALA168
A	GLY169
A	GLY170
A	VAL277
A	ALA312
A	GLY313
A	THR335
A	ASN336
A	HIS337
A	ASP343

site_id	AC9
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEC B 601

Chain	Residue
B	SER58
B	SER62
B	HIS63
B	LEU64
B	TYR83
B	CYS84
B	CYS87
B	HIS88
B	PHE90
B	LEU166
B	ALA168
B	VAL373
B	GLY433
B	TYR434
B	LEU437
B	HEC602

site_id	BC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEC B 602

Chain	Residue
B	HIS42
B	GLY43
B	LEU45
B	LEU48
B	PRO59
B	HIS60
B	ILE68
B	ALA69
B	CYS70
B	CYS73
B	HIS74
B	ASP93
B	MET94
B	PRO95
B	HEC601
B	HEC604
D	GLU359
D	TYR360

site_id	BC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE HEC B 603

Chain	Residue
B	ALA6
B	GLY14
B	CYS15
B	CYS18
B	HIS19
B	LYS23
B	GLY24
B	GLY25
B	THR71
B	LYS75
B	GLY76
B	HIS77
B	TYR297

site_id	BC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC B 604

Chain	Residue
B	LEU5
B	PHE8
B	HIS9
B	SER17
B	GLN37
B	CYS38
B	CYS41
B	HIS42
B	HIS74
B	PRO95
B	HEC602
D	ARG200
D	TYR325
D	ASP326
D	PRO327
D	TYR360
D	HOH925

site_id	BC4
Number of Residues	36
Details	BINDING SITE FOR RESIDUE FAD B 700

Chain	Residue
B	ILE131
B	GLY132
B	SER133
B	GLY134
B	ALA136
B	GLU155
B	LYS156
B	GLU157
B	GLY162
B	ASN163
B	THR164
B	ALA167
B	GLY169
B	GLY170
B	ARG276
B	VAL277
B	ALA312
B	GLY313
B	THR335
B	ASN336
B	HIS337
B	ASP343
B	MET374
B	HIS503
B	HIS504
B	GLY533
B	GLU534
B	ARG544
B	GLY547
B	ASN548
B	ALA549
B	ILE550
B	ILE553
B	SO4714
B	HOH728
B	HOH733

site_id	BC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC C 601

Chain	Residue
C	SER58
C	SER62
C	HIS63
C	LEU64
C	TYR83
C	CYS84
C	CYS87
C	HIS88
C	PHE90
C	LEU166
C	ALA168
C	HIS337
C	VAL373
C	GLY433
C	TYR434
C	HIS436
C	LEU437

site_id	BC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC C 602

Chain	Residue
A	TYR360
C	HIS42
C	GLY43
C	LEU45
C	LEU48
C	PRO59
C	HIS60
C	ILE68
C	ALA69
C	CYS70
C	CYS73
C	HIS74
C	ASP93
C	MET94
C	HEC604

site_id	BC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEC C 603

Chain	Residue
C	ALA6
C	GLY14
C	CYS15
C	CYS18
C	HIS19
C	LYS23
C	GLY24
C	VAL26
C	LYS75
C	GLY76
C	HIS77
C	TYR297

site_id	BC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC C 604

Chain	Residue
A	ARG200
A	TYR325
A	PRO327
A	GLU359
A	TYR360
C	LEU5
C	PHE8
C	HIS9
C	SER17
C	GLN37
C	CYS38
C	CYS41
C	HIS42
C	HIS74
C	HEC602

site_id	BC9
Number of Residues	38
Details	BINDING SITE FOR RESIDUE FAD C 800

Chain	Residue
C	ILE131
C	GLY132
C	GLY134
C	GLY135
C	ALA136
C	LEU154
C	GLU155
C	LYS156
C	GLY162
C	ASN163
C	THR164
C	ALA167
C	ALA168
C	GLY169
C	GLY170
C	ARG276
C	VAL277
C	ALA312
C	THR335
C	ASN336
C	HIS337
C	ASP343
C	MET374
C	HIS503
C	HIS504
C	GLY533
C	GLU534
C	ARG544
C	GLY547
C	ASN548
C	ALA549
C	ILE550
C	ILE553
C	SO4814
C	HOH822
C	HOH826
C	HOH831
C	HOH844

site_id	CC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC D 601

Chain	Residue
D	VAL57
D	SER58
D	SER62
D	HIS63
D	LEU64
D	TYR83
D	CYS84
D	CYS87
D	HIS88
D	LEU166
D	ALA168
D	HIS337
D	VAL373
D	GLY433
D	LEU437

site_id	CC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC D 602

Chain	Residue
B	TYR360
D	HIS42
D	LEU45
D	LEU48
D	PRO59
D	HIS60
D	ILE68
D	ALA69
D	CYS70
D	CYS73
D	HIS74
D	ASP93
D	MET94
D	HEC604

site_id	CC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC D 603

Chain	Residue
D	ALA6
D	GLY14
D	CYS15
D	CYS18
D	HIS19
D	LYS23
D	GLY24
D	GLY25
D	LEU31
D	THR71
D	LYS75
D	GLY76
D	HIS77
D	TYR297
D	HEC604

site_id	CC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEC D 604

Chain	Residue
B	ARG200
B	TYR325
B	ASP326
B	TYR360
D	LEU5
D	PHE8
D	HIS9
D	MET12
D	SER17
D	GLN37
D	CYS38
D	CYS41
D	HIS42
D	HIS74
D	HEC602
D	HEC603

site_id	CC5
Number of Residues	37
Details	BINDING SITE FOR RESIDUE FAD D 900

Chain	Residue
D	ILE131
D	GLY132
D	GLY134
D	GLY135
D	ALA136
D	GLU155
D	LYS156
D	GLU157
D	GLY162
D	ASN163
D	THR164
D	ALA167
D	GLY169
D	GLY170
D	VAL277
D	ALA312
D	GLY313
D	THR335
D	ASN336
D	HIS337
D	ASP343
D	HIS503
D	HIS504
D	GLY533
D	GLU534
D	ARG544
D	GLY547
D	ASN548
D	ALA549
D	ILE550
D	ILE553
D	SO4914
D	HOH921
D	HOH922
D	HOH923
D	HOH924
D	HOH931

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000250\|UniProtKB:P0C278

Chain	Residue	Details
A	ARG401
B	ARG401
C	ARG401
D	ARG401

site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: axial binding residue => ECO:0000269\|PubMed:10581551, ECO:0007744\|PDB:1D4C

Chain	Residue	Details
A	HIS9
B	HIS19
B	HIS42
B	HIS60
B	HIS63
B	HIS74
B	HIS77
B	HIS88
C	HIS9
C	HIS19
C	HIS42
A	HIS19
C	HIS60
C	HIS63
C	HIS74
C	HIS77
C	HIS88
D	HIS9
D	HIS19
D	HIS42
D	HIS60
D	HIS63
A	HIS42
D	HIS74
D	HIS77
D	HIS88
A	HIS60
A	HIS63
A	HIS74
A	HIS77
A	HIS88
B	HIS9

site_id	SWS_FT_FI3
Number of Residues	32
Details	BINDING: covalent => ECO:0000269\|PubMed:10581551, ECO:0007744\|PDB:1D4C

Chain	Residue	Details
A	CYS15
B	CYS18
B	CYS38
B	CYS41
B	CYS70
B	CYS73
B	CYS84
B	CYS87
C	CYS15
C	CYS18
C	CYS38
A	CYS18
C	CYS41
C	CYS70
C	CYS73
C	CYS84
C	CYS87
D	CYS15
D	CYS18
D	CYS38
D	CYS41
D	CYS70
A	CYS38
D	CYS73
D	CYS84
D	CYS87
A	CYS41
A	CYS70
A	CYS73
A	CYS84
A	CYS87
B	CYS15

site_id	SWS_FT_FI4
Number of Residues	64
Details	BINDING: BINDING => ECO:0000269\|PubMed:10581551, ECO:0007744\|PDB:1D4C

Chain	Residue	Details
A	GLY76
A	VAL277
A	ASP343
A	TYR360
A	HIS504
A	GLU534
A	ALA549
A	ILE550
B	GLY76
B	ASP93
B	ALA136
A	ASP93
B	GLU155
B	ASN163
B	THR164
B	ALA168
B	GLY170
B	ARG200
B	VAL277
B	ASP343
B	TYR360
B	HIS504
A	ALA136
B	GLU534
B	ALA549
B	ILE550
C	GLY76
C	ASP93
C	ALA136
C	GLU155
C	ASN163
C	THR164
C	ALA168
A	GLU155
C	GLY170
C	ARG200
C	VAL277
C	ASP343
C	TYR360
C	HIS504
C	GLU534
C	ALA549
C	ILE550
D	GLY76
A	ASN163
D	ASP93
D	ALA136
D	GLU155
D	ASN163
D	THR164
D	ALA168
D	GLY170
D	ARG200
D	VAL277
D	ASP343
A	THR164
D	TYR360
D	HIS504
D	GLU534
D	ALA549
D	ILE550
A	ALA168
A	GLY170
A	ARG200

site_id	SWS_FT_FI5
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269\|PubMed:10581551, ECO:0007744\|PDB:1D4D

Chain	Residue	Details
A	GLY169
B	THR376
B	GLU377
B	HIS503
B	ARG544
B	GLY547
C	GLY169
C	HIS364
C	THR376
C	GLU377
C	HIS503
A	HIS364
C	ARG544
C	GLY547
D	GLY169
D	HIS364
D	THR376
D	GLU377
D	HIS503
D	ARG544
D	GLY547
A	THR376
A	GLU377
A	HIS503
A	ARG544
A	GLY547
B	GLY169
B	HIS364

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)