1D2K

C. IMMITIS CHITINASE 1 AT 2.2 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004568	molecular_function	chitinase activity
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0006032	biological_process	chitin catabolic process
A	0008061	molecular_function	chitin binding
A	0008843	molecular_function	endochitinase activity
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds

Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGIDIDwE

Chain	Residue	Details
A	PHE163-GLU171

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	GLU171

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	GLY102
A	GLY129
A	TYR172
A	MET237
A	TRP378

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Transition state stabilizer

Chain	Residue	Details
A	ASP169

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN387

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1ctn

Chain	Residue	Details
A	ASP169
A	TYR239
A	GLU171

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1ctn

Chain	Residue	Details
A	ASP169
A	GLU171

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1ctn

Chain	Residue	Details
A	ASP167
A	GLU171

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