Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 850 |
| Chain | Residue |
| A | GLN249 |
| A | TYR359 |
| A | GLU363 |
| A | ASN368 |
| A | HOH1008 |
| A | HOH1030 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 860 |
| Chain | Residue |
| A | HOH972 |
| A | HOH1091 |
| A | HOH1147 |
| A | TRP358 |
| A | VAL420 |
| A | SER428 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 851 |
| Chain | Residue |
| B | GLN249 |
| B | TYR359 |
| B | GLU363 |
| B | ASN368 |
| B | HOH956 |
| B | HOH1129 |
| B | HOH1130 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 861 |
| Chain | Residue |
| B | GLN191 |
| B | TRP358 |
| B | VAL420 |
| B | SER428 |
| B | HEM500 |
| B | HOH1138 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS96 |
| A | CYS101 |
| B | CYS96 |
| B | CYS101 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HEM A 500 |
| Chain | Residue |
| A | TRP180 |
| A | ARG185 |
| A | CYS186 |
| A | PHE355 |
| A | SER356 |
| A | TRP358 |
| A | TRP449 |
| A | PHE475 |
| A | TYR477 |
| A | INE760 |
| A | HOH1008 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE INE A 760 |
| Chain | Residue |
| A | PRO336 |
| A | PHE355 |
| A | GLY357 |
| A | TRP358 |
| A | TYR359 |
| A | MET360 |
| A | GLU363 |
| A | HEM500 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE INE B 765 |
| Chain | Residue |
| A | SER104 |
| A | ARG367 |
| A | TRP449 |
| A | GOL880 |
| A | HOH1035 |
| B | TRP76 |
| B | TRP447 |
| B | PHE462 |
| B | HIS463 |
| B | GLN464 |
| B | GLU465 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CAD A 950 |
| Chain | Residue |
| A | CYS384 |
| A | GLN437 |
| A | ARG440 |
| A | GLY441 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM B 500 |
| Chain | Residue |
| B | TRP180 |
| B | ARG185 |
| B | CYS186 |
| B | PHE355 |
| B | SER356 |
| B | TRP358 |
| B | GLU363 |
| B | TRP449 |
| B | TYR477 |
| B | INE761 |
| B | ACT861 |
| B | HOH1130 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE INE B 761 |
| Chain | Residue |
| B | PRO336 |
| B | PHE355 |
| B | SER356 |
| B | GLY357 |
| B | TRP358 |
| B | TYR359 |
| B | MET360 |
| B | GLU363 |
| B | HEM500 |
| site_id | BC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE INE A 766 |
| Chain | Residue |
| A | TRP76 |
| A | TRP447 |
| A | PHE462 |
| A | HIS463 |
| A | GLN464 |
| A | GLU465 |
| B | SER104 |
| B | ARG367 |
| B | TRP449 |
| B | HOH1016 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CAD B 951 |
| Chain | Residue |
| B | TYR83 |
| B | CYS384 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 880 |
| Chain | Residue |
| B | INE765 |
| A | ARG367 |
| A | HIS373 |
| A | HOH1035 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 881 |
| Chain | Residue |
| A | TRP76 |
| B | HIS373 |
| B | HOH1007 |
| B | HOH1016 |
| B | HOH1091 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG185-TRP192 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS96 | |
| A | CYS101 | |
| B | CYS96 | |
| B | CYS101 | |
| Chain | Residue | Details |
| A | SER104 | |
| A | TYR477 | |
| B | SER104 | |
| B | GLN249 | |
| B | TRP358 | |
| B | TYR359 | |
| B | GLU363 | |
| B | ASN368 | |
| B | ALA448 | |
| B | TRP449 | |
| B | PHE462 | |
| A | GLN249 | |
| B | TYR477 | |
| A | TRP358 | |
| A | TYR359 | |
| A | GLU363 | |
| A | ASN368 | |
| A | ALA448 | |
| A | TRP449 | |
| A | PHE462 | |
| Chain | Residue | Details |
| A | CYS186 | |
| B | CYS186 | |
| Chain | Residue | Details |
| A | SER116 | |
| B | SER116 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| A | CYS186 | |
| A | ARG189 | |
| A | GLU363 | |
| A | TRP358 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| B | CYS186 | |
| B | ARG189 | |
| B | GLU363 | |
| B | TRP358 | |
