1CY5

CRYSTAL STRUCTURE OF THE APAF-1 CARD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002020	molecular_function	protease binding
A	0042981	biological_process	regulation of apoptotic process
A	0070513	molecular_function	death domain binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 101

Chain	Residue
A	GLU17
A	GLN50
A	ASP64
A	ASP66
A	HOH201
A	HOH290

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 102

Chain	Residue
A	HIS88
A	HOH282
A	ASP27
A	ILE30
A	GLU40

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 103

Chain	Residue
A	HIS28
A	ASP32
A	HOH299

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 104

Chain	Residue
A	GLU41
A	HIS77

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 105

Chain	Residue
A	HIS28
A	GLU78
A	HOH305
A	HOH306

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BME A 99

Chain	Residue
A	CYS8
A	HIS12
A	ASP82
A	LEU86
A	GLY90
A	HOH207

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